ArticleJournal of virology2008
Genome analysis of a Glossina pallidipes salivary gland hypertrophy virus reveals a novel, large, double-stranded circular DNA virus.
Article in Journal of virology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 81 citations in OpenAlex.
- Discovery of a novel double-stranded DNA virus associated with ant labial gland disease reveals its long-term interaction with ants.Journal of virology · 2025Article
- A novel and diverse family of filamentous DNA viruses associated with parasitic wasps.Virus evolution · 2024Article
- Interactions between Glossina pallidipes salivary gland hypertrophy virus and tsetse endosymbionts in wild tsetse populations.Parasites & vectors · 2022Article
- Conserved Viral Transcription Plays a Key Role in Virus-Like Particle Production of the Parasitoid WaspJournal of virology · 2022Article
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- Review
- Coevolution of hytrosaviruses and host immune responses.BMC microbiology · 2018Review
- RNA interference-based antiviral immune response against the salivary gland hypertrophy virus in Glossina pallidipes.BMC microbiology · 2018Article
- Hytrosavirus genetic diversity and eco-regional spread in Glossina species.BMC microbiology · 2018Article
- Expression Profile ofFrontiers in microbiology · 2018Article
- Responses of the Housefly,Frontiers in microbiology · 2017Article
- Genome Sequencing of the Behavior Manipulating Virus LbFV Reveals a Possible New Virus Family.Genome biology and evolution · 2016Article
- Comprehensive annotation of Glossina pallidipes salivary gland hypertrophy virus from Ethiopian tsetse flies: a proteogenomics approach.The Journal of general virology · 2016Article
- Comparative Analysis of Salivary Gland Proteomes of Two Glossina Species that Exhibit Differential Hytrosavirus Pathologies.Frontiers in microbiology · 2016Article
- The genome of the nucleopolyhedrosis-causing virus from Tipula oleracea sheds new light on the Nudiviridae family.Journal of virology · 2015Article
- Article
- Brown planthopper nudivirus DNA integrated in its host genome.Journal of virology · 2014Article
- Genome sequence of the tsetse fly (Glossina morsitans): vector of African trypanosomiasis.Science (New York, N.Y.) · 2014Article
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Corrections and comments
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Authors and funding
8 authors at 4 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several species of tsetse flies can be infected by the Glossina pallidipes salivary gland hypertrophy virus (GpSGHV). Infection causes salivary gland hypertrophy and also significantly reduces the fecundity of the infected flies. To better understand the molecular basis underlying the pathogenesis of this unusual virus, we sequenced and analyzed its genome. The GpSGHV genome is a double-stranded circular DNA molecule of 190,032 bp containing 160 nonoverlapping open reading frames (ORFs), which are distributed equally on both strands with a gene density of one per 1.2 kb. It has a high A+T content of 72%. About 3% of the GpSGHV genome is composed of 15 sequence repeats, distributed throughout the genome. Although sharing the same morphological features (enveloped rod-shaped nucleocapsid) as baculoviruses, nudiviruses, and nimaviruses, analysis of its genome revealed that GpSGHV differs significantly from these viruses at the level of its genes. Sequence comparisons indicated that only 23% of GpSGHV genes displayed moderate homologies to genes from other invertebrate viruses, principally baculoviruses and entomopoxviruses. Most strikingly, the GpSGHV genome encodes homologues to the four baculoviral per os infectivity factors (p74 [pif-0], pif-1, pif-2, and pif-3). The DNA polymerase encoded by GpSGHV is of type B and appears to be phylogenetically distant from all DNA polymerases encoded by large double-stranded DNA viruses. The majority of the remaining ORFs could not be assigned by sequence comparison. Furthermore, no homologues to DNA-dependent RNA polymerase subunits were detected. Taken together, these data indicate that GpSGHV is the prototype member of a novel group of insect viruses.
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