ArticleAJNR. American journal of neuroradiology2008
Posterior reversible encephalopathy syndrome after solid organ transplantation.
Article in AJNR. American journal of neuroradiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
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Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 225 citations in OpenAlex.
- Neurocognitive-neurological complications of liver transplantation: a review.Metabolic brain disease · 2010Pooled it
- [Extrapulmonary sarcoidosis with multiorgan involvement: a complex case with renal, neurological, and gastrointestinal manifestations].Innere Medizin (Heidelberg, Germany) · 2026Article
- Neurotoxicity of Calcineurin Inhibitors.Annals of Indian Academy of Neurology · 2025Article
- Posterior Reversible Leukoencephalopathy Syndrome and Disseminated Varicella-Zoster Virus Infection After Kidney Transplantation.IJU case reports · 2025Article
- Article
- Connective tissue disease is associated with the risk of posterior reversible encephalopathy syndrome following lung transplantation in Korea.Acute and critical care · 2025Article
- Successful Treatment with Mycophenolate Mofetil in a Patieint with Anti-MDA 5 Antibody-positive Interstitial Lung Disease and Posterior Reversible Encephalopathy Syndrome.Internal medicine (Tokyo, Japan) · 2025Article
- Tacrolimus-Related Posterior Reversible Encephalopathy Syndrome in a Postlung Transplant Patient: A Case Report.Case reports in critical care · 2025Article
- Posterior Reversible Encephalopathy Syndrome Associated with L-Asparaginase Treatment in Children: Literature Review and Six Case Reports.Current drug safety · 2025Review
- Clinical features and outcomes of posterior reversible encephalopathy syndrome after heart transplantation: a case series.Clinical transplantation and research · 2024Article
- Article
- Acute Kidney Injury in Kidney Transplant Patients in Intensive Care Unit: From Pathogenesis to Clinical Management.Biomedicines · 2023Review
- Neuropsychiatric Symptoms after Liver Transplantation in a 65-Year-Old Male Patient.Brain sciences · 2022Article
- Article
- An Unusual Presentation of Posterior Reversible Encephalopathy Syndrome Following Liver Transplantation.Transplantation direct · 2022Article
- Late presentation of posterior reversible encephalopathy syndrome following liver transplantation in the setting of tacrolimus and cannabis use.Canadian liver journal · 2022Article
- Fatal Thrombotic Microangiopathy and Posterior Reversible Encephalopathy Syndrome in a Patient with Anti-melanoma Differentiation-associated Gene 5 Antibody-positive Dermatomyositis.Internal medicine (Tokyo, Japan) · 2021Article
- Neuroimaging findings of posterior reversible encephalopathy syndrome (PRES) following haematopoietic stem cell transplantation in paediatric recipients.BMC pediatrics · 2021Article
- Article
- Immunosuppression-related neurological disorders in kidney transplantation.Journal of nephrology · 2021Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposePosterior reversible encephalopathy syndrome (PRES) is known to occur after solid organ transplantation (SOT), potentially associated with cyclosporine and tacrolimus. In this study, we assess the frequency and clinical and imaging characteristics of PRES after SOT. MATERIALS AND
methodsWe identified 27 patients (13 men and 14 women; age range, 22-72 years) who developed PRES after SOT. Features noted included SOT subtype, incidence and timing of PRES, infection and rejection, mean arterial pressure (MAP), and toxicity brain edema.
resultsPRES developed in 21 (0.49%) of 4222 patients who underwent transplantation within the study period (no significant difference among SOT subtypes). Transplantation was performed in 5 patients before the study period, and 1 patient underwent transplantation elsewhere. In consideration of all 27 patients, PRES typically developed in the first 2 months in patients who had SOT of the liver (9 of 10 patients) and was associated with cytomegalovirus (CMV), mild rejection, or systemic bacterial infection. PRES also typically developed after 1 year in patients who had SOT of the kidney (8 of 9 patients) and was associated with moderate rejection or bacterial infection. Toxicity MAP was significantly lower (P < .001) in liver transplants (average MAP, 104.8 +/- 16 mm Hg) compared with that in kidney transplants (average MAP, 143 +/- 20 mm Hg). Toxicity brain edema was significantly greater (P < .001) in patients who had liver transplants and developed PRES compared with patients who had undergone kidney transplants despite severe hypertension in those who had the kidney transplants.
conclusionPatients who had undergone SOTs have a similar low incidence of developing PRES. Differences between those who have had liver and kidney transplants included time after transplant, toxicity MAP, and PRES vasogenic edema noted at presentation. In patients who have undergone kidney transplants, severely elevated MAP was associated with reduced, not greater, brain edema.
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