ArticleAJNR. American journal of neuroradiology2008
Accuracy of the Alberta Stroke Program Early CT Score during the first 3 hours of middle cerebral artery stroke: comparison of noncontrast CT, CT angiography source images, and CT perfusion.
Article in AJNR. American journal of neuroradiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.
- Pooled it
- To do or not to do; dilemma of intra-arterial revascularization in acute ischemic stroke.PloS one · 2014Trial
- Baseline imaging for determining infarct core in patients with acute ischemic stroke: noncontrast computed tomography vs computed tomography perfusion.Neuroradiology · 2026Article
- Dual-Energy CT in Acute Stroke: Could Non-Contrast CT Be Replaced by Virtual Non-Contrast CT? A Feasibility Study.Journal of clinical medicine · 2024Article
- Predictive value of ischemia location on multimodal CT in thrombectomy-treated patients.The neuroradiology journal · 2023Article
- Improving the diagnosis of acute ischemic stroke on non-contrast CT using deep learning: a multicenter study.Insights into imaging · 2022Article
- Diagnostic accuracy of using Alberta Stroke Program Early Computed Tomography Score on CT perfusion map to predict a target mismatch in patients with acute ischemic stroke.Neuroradiology · 2022Article
- Mismatch between automated CTP and ASPECTS score in patients with anterior large vessel occlusion.Clinical neurology and neurosurgery · 2020Article
- Imaging Ischemic and Hemorrhagic Disease of the Brain in Dogs.Frontiers in veterinary science · 2020Review
- Article
- Primary Endovascular Treatment of Acute Ischemic Stroke Using Stent Retrievers: Initial Egyptian Experience.Journal of vascular and interventional neurology · 2017Article
- Computed Tomography Perfusion Alberta Stroke Program Early Computed Tomography Score Is Associated with Hemorrhagic Transformation after Acute Cardioembolic Stroke.Frontiers in neurology · 2017Article
- Performance of CT ASPECTS and Collateral Score in Risk Stratification: Can Target Perfusion Profiles Be Predicted without Perfusion Imaging?AJNR. American journal of neuroradiology · 2016Article
- Randomized trials of endovascular therapy for stroke--impact on stroke care.Nature reviews. Neurology · 2016Review
- Dynamic Angiography and Perfusion Imaging Using Flat Detector CT in the Angiography Suite: A Pilot Study in Patients with Acute Middle Cerebral Artery Occlusions.AJNR. American journal of neuroradiology · 2015Article
- Cerebral CT angiography and CT perfusion in acute stroke detection: a systematic review of diagnostic value.Quantitative imaging in medicine and surgery · 2014Review
- Letter to the Editor. CT angiography source-images and CT perfusion: are they complementary tools for ischemic stroke evaluation? Response to: reliability of CT perfusion in the evaluation of ischaemic penumbra.The neuroradiology journal · 2014Article
- Computer-aided diagnosis of hyperacute stroke with thrombolysis decision support using a contralateral comparative method of CT image analysis.Journal of digital imaging · 2014Article
- Response to letter to the editor. "CT angiography source-images and CT perfusion: are they complementary tools for ischemic stroke evaluation?".The neuroradiology journal · 2014Article
- Time-resolved assessment of collateral flow using 4D CT angiography in large-vessel occlusion stroke.European radiology · 2014Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe Alberta Stroke Program Early CT Score (ASPECTS) is a reliable method of delineating the extent of middle cerebral artery (MCA) stroke. Our aim was to retrospectively compare the accuracy of ASPECTS on noncontrast CT, CT angiography (CTA) source images, and CT perfusion maps of cerebral blood volume (CBV) during the first 3 hours of middle cerebral artery (MCA) stroke. MATERIALS AND
methodsFirst-time patients with MCA stroke who presented <3 hours from symptom onset and were evaluated by noncontrast CT/CTA/CT perfusion, had confirmed acute nonlacunar MCA infarct on diffusion-weighted MR imaging (DWI) within 7 days, and had follow-up angiography were included. Patients were excluded for persistent MCA occlusion or stenosis. Two raters through consensus assigned an ASPECTS on the noncontrast CT, CTA source images, and the section-selective (2 x 12 mm coverage) CT perfusion CBV maps. ASPECTS on follow-up DWI served as the reference standard. For each CT technique, the detection rates of regional infarction, the mean ASPECTS, and the linear correlation to final ASPECTS were determined and compared. P values <.05 were considered significant.
resultsTwenty-eight patients satisfied the criteria with DWI performed at a mean of 50.3 hours (range, 22-125 hours) post-CT imaging. Of 280 ASPECTS regions, 100 were infarcted on DWI. The accuracy of noncontrast CT, CTA source images, and CT perfusion CBV for detecting regional infarct was 80.0%, 84.3%, and 96.8%, respectively (P < .0001). The mean ASPECTSs of noncontrast CT, CTA source images, CT perfusion CBV, and DWI were 8.4 +/- 1.8, 8.0 +/- 1.8, 6.8 +/- 1.9, and 6.5 +/- 1.8, respectively. The mean noncontrast CT and CTA source image ASPECTS was different from that of DWI (P < .05). Correlation of noncontrast CT, CTA source images, and CT perfusion CBV ASPECTS with final ASPECTS was r(2) = 0.34, r(2) = 0.42, and r(2) = 0.91, respectively.
conclusionIn a retrospective cohort of MCA infarcts imaged <3 hours from stroke onset, ASPECTS was most accurately determined on CT perfusion CBV maps.
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