ReviewInfant behavior & development2008
Breastfeeding and antidepressants.
Review in Infant behavior & development, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- The impact of home care interventions on postpartum depression symptoms: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2026Pooled it
- Selective serotonin reuptake inhibitors and preeclampsia: A quality assessment and meta-analysis.Pregnancy hypertension · 2022Pooled it
- Cognitive Outcomes of Children Exposed to Selective Serotonin Reuptake Inhibitors Through Breast Milk.JAMA network open · 2025Article
- Screening for and Treating Postpartum Depression and Psychosis: A Cost-Effectiveness Analysis.Maternal and child health journal · 2017Article
- Depression During Pregnancy and Postpartum.Current psychiatry reports · 2016Review
- Efficacy of light therapy for perinatal depression: a review.Journal of physiological anthropology · 2012Review
- Treatment of postpartum depression: clinical, psychological and pharmacological options.International journal of women's health · 2010Article
- The impact of mood disorders and their treatment on the pregnant woman, the fetus, and the infant.Current psychiatry reports · 2010Review
- Postpartum depression effects on early interactions, parenting, and safety practices: a review.Infant behavior & development · 2010Review
- The Relationship Among Breastfeeding, Postpartum Depression, and Postpartum Weight in Mexican American Women.Journal of obstetric, gynecologic, and neonatal nursing : JOGNNArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Although a large literature supports the benefits of breastfeeding, this review suggests that breastfeeding is less common among postpartum depressed women, even though their infants benefit from the breastfeeding. Depressed mothers, in part, do not breastfeed because of their concern about potentially negative effects of antidepressants on their infants. Although sertraline (Zoloft) and paroxetine (Paxol) concentrations are not detectable in infants' sera, fluoxetine (Prozac) and citalopram (Celexa) do have detectable levels. Unfortunately these findings are not definitive because they are based on very small sample, uncontrolled studies. As in the literature on prenatal antidepressant effects, the question still remains whether the antidepressants or the untreated depression itself has more negative effects on the infant. It is possible that the positive effects of breastfeeding may outweigh the positive effects of the antidepressants for both the mother and the infant. In addition, some alternative therapies may substitute or attenuate the effects of antidepressants, such as vagal stimulation or massage therapy, both therapies being noted to reduce depression. Further studies of this kind are needed to determine the optimal course of therapy for the benefit of the depressed, breastfeeding mother and the breastfed infant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.