Evidence map›Paper›PMID 18272019›Full record

ArticleEpidemiology and infection2008

Scenarios of diffusion and control of an influenza pandemic in Italy.

C Rizzo, A Lunelli, A Pugliese, A Bella, P Manfredi, G Scalia Tomba, M Iannelli, M L Ciofi degli Atti

Abstract read
In one paragraph

Article in Epidemiology and infection, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

C RizzoNational Centre for Epidemiology Surveillance and Health Promotion, Istituto Superiore di Sanità, Rome, Italy. caterina.rizzo@iss.it
A Lunelli
A Pugliese
A Bella
P Manfredi
G Scalia Tomba
M Iannelli
M L Ciofi degli Atti

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To predict the spread of a pandemic strain of influenza virus in Italy and the impact of control measures, we developed a susceptible-exposed, but not yet infectious-infectious-recovered, and no longer susceptible (SEIR) deterministic model with a stochastic simulation component. We modelled the impact of control measures such as vaccination, antiviral prophylaxis and social distancing measures. In the absence of control measures, the epidemic peak would be reached about 4 months after the importation of the first cases in Italy, and the epidemic would last about 7 months. When combined, the control measures would reduce the cumulative attack rate to about 4.2%, at best, although this would require an extremely high number of treated individuals. In accordance with international findings, our results highlight the need to respond to a pandemic with a combination of control measures.

Indexed as

Models, StatisticalAdolescentAdultAgedAntiviral AgentsChildChild, PreschoolComputer SimulationDisease OutbreaksHumansInfantInfluenza A Virus, H5N1 SubtypeInfluenza, HumanInfluenza VaccinesItalyMiddle AgedAntiviral AgentsInfluenza Vaccines

Identifiers

PMID18272019
PMCPMC2870775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.