Trial reportBJOG : an international journal of obstetrics and gynaecology2008
Quality of life and acceptability of medical versus surgical management of early pregnancy failure.
Trial report in BJOG : an international journal of obstetrics and gynaecology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Methods for managing miscarriage: a network meta-analysis.The Cochrane database of systematic reviews · 2021Pooled it
- Medical treatment for early fetal death (less than 24 weeks).The Cochrane database of systematic reviews · 2019Pooled it
- Medical treatments for incomplete miscarriage.The Cochrane database of systematic reviews · 2017Pooled it
- Medical treatments for incomplete miscarriage (less than 24 weeks).The Cochrane database of systematic reviews · 2010Pooled it
- Medical treatment for early fetal death (less than 24 weeks).The Cochrane database of systematic reviews · 2006Pooled it
- Serum biomarkers may help predict successful misoprostol management of early pregnancy failure.Reproductive biology · 2015Trial
- Simplified follow-up after medical abortion using a low-sensitivity urinary pregnancy test and a pictorial instruction sheet in Rajasthan, India--study protocol and intervention adaptation of a randomised control trial.BMC women's health · 2014Trial
- A cost-effectiveness analysis of surgical versus medical management of early pregnancy loss.Fertility and sterility · 2012Trial
- Quality of life and acceptability of medical versus surgical management of early pregnancy failure.BJOG : an international journal of obstetrics and gynaecology · 2008Trial
- Women's physical health around live births and pregnancy losses: a longitudinal study.European journal of public health · 2025Article
- Treatment of early pregnancy failure: does induced abortion training affect later practices?American journal of obstetrics and gynecology · 2011Article
- Provider knowledge, attitudes, and treatment preferences for early pregnancy failure.American journal of obstetrics and gynecology · 2010Article
- Management of early pregnancy failure.Reviews in obstetrics & gynecology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThis study compares quality of life (QOL) and acceptability of medical versus surgical treatment of early pregnancy failure (EPF).
designA randomised clinical trial of treatment for EPF compared misoprostol vaginally versus vacuum aspiration (VA).
settingA multisite trial at four US Urban University Hospitals. POPULATION: A total of 652 women with an EPF were randomised to treatment.
methodsParticipants completed a daily symptom diary and a questionnaire 2 weeks after treatment.
main outcome measuresThe questionnaire assessment included subscales of the Short Form-36 Health Survey Revised for QOL and measures of wellbeing, recovery difficulties, and treatment acceptability.
resultsThe two groups did not differ in mean scores for QOL except bodily pain; medical treatment was associated with higher levels of bodily pain than VA (P < 0.001). Success of treatment was not related to QOL, but acceptability of the procedure was decreased for medical therapy if unsuccessful (P = 0.003). Type of treatment was not associated with differences in recovery, and the two groups reported similar acceptability except for cramping (P = 0.02), bleeding (P < 0.001), and symptom duration (P = 0.03).
conclusionsDespite reporting greater pain and lower acceptability of treatment-related symptoms, QOL and treatment acceptability were similar for medical and surgical treatment of EPF. Acceptability, but not QOL, was influenced by success or failure of medical management.
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