Evidence map›Paper›PMID 18271593›Full record

ArticleJournal of the American Chemical Society2008

Stabilization of the collagen triple helix by O-methylation of hydroxyproline residues.

Frank W Kotch, Ilia A Guzei, Ronald T Raines

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Trial
  2. Article
  3. Functions of prolyl hydroxylation in elastin.The Journal of biological chemistry · 2026
    Article
  4. Review
  5. Around the collagen triple helix: an introduction to studying associated genetic and acquired diseases.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Advances in Plant-Derived Scaffold Proteins.Frontiers in plant science · 2020
    Review
  19. Article
  20. Multicomponent peptide assemblies.Chemical Society reviews · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Frank W KotchDepartment of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.
Ilia A Guzei
Ronald T Raines

Funding

COLLAGEN STRUCTURE AND STABILITY IN VITRO AND IN VIVOR01AR044276 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI RAINES, RONALD T · 1996 to 2017
$5.6M
Chemistry and Biology of CollagenR56AR044276 · NIAMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI RAINES, RONALD T · 2019 to 2020
$826k
Invasion and Association of Tethered Collagen MimeticsF32AR050881 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI KOTCH, FRANK W · 2004 to 2006
$134k
ACQUISITION OF MASS SPECTROMETER FOR CORE FACILITYS10RR013790 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI RAINES, RONALD T · 1999 to 1999
–
NCRR NIH HHS RR13790NCRR NIH HHS S10 RR013790NIAMS NIH HHS AR044276NIAMS NIH HHS AR050881NIAMS NIH HHS F32 AR050881NIAMS NIH HHS R01 AR044276NIAMS NIH HHS R56 AR044276
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CollagenCrystallography, X-RayHydroxyprolineMethylationModels, ChemicalModels, MolecularOligopeptidesProtein ConformationProtein Structure, SecondaryThermodynamicsCollagenHydroxyprolineOligopeptides

Identifiers

PMID18271593
PMCPMC2802593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.