ArticleSurgical endoscopy2008
Laparoscopic sleeve gastrectomy with ileal transposition (SGIT): A new surgical procedure as effective as gastric bypass for weight control in a porcine model.
Article in Surgical endoscopy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Short-term and mid-term control of type 2 diabetes mellitus by laparoscopic sleeve gastrectomy with ileal interposition.World journal of surgery · 2011Trial
- New intragastric sleeve technique reduces adipose tissue in pig experimental model: tomographic study.Scientific reports · 2020Article
- Technical Feasibility of a Murine Model of Sleeve Gastrectomy with Ileal Transposition.Obesity surgery · 2019Article
- Long-term Effect of Ileal Transposition on Adipokine Serum Level in Zucker (Orl)-Lepr(fa) Fatty Rats.Obesity surgery · 2015Article
- Effect of three different bariatric obesity surgery procedures on nutrient and energy digestibility using a swine experimental model.Experimental biology and medicine (Maywood, N.J.) · 2015Article
- Ileal interposition surgery for treatment of type 2 diabetes mellitus-pros and cons.Journal of diabetes and metabolic disorders · 2015Article
- From gut changes to type 2 diabetes remission after gastric bypass surgeries.Frontiers of medicine · 2013Review
- Type 2 diabetes control in a nonobese rat model using sleeve gastrectomy with duodenal-jejunal bypass (SGDJB).Obesity surgery · 2012Article
- Sleeve gastrectomy plus side-to-side jejunoileal anastomosis for the treatment of morbid obesity and metabolic diseases: a promising operation.Obesity surgery · 2012Article
- Ileal interposition with sleeve gastrectomy for treatment of type 2 diabetes mellitus.Indian journal of endocrinology and metabolism · 2012Article
- Diabetic and bariatric surgery: a review of the recent trends.Surgical endoscopy · 2012Review
- Sleeve gastrectomy induces weight loss in diet-induced obese rats even if high-fat feeding is continued.Obesity surgery · 2011Article
- Sleeve gastrectomy with ileal transposition (SGIT) induces a significant weight loss and diabetes improvement without exclusion of the proximal intestine.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2011Article
- Surgical treatment of morbid obesity: mid-term outcomes of the laparoscopic ileal interposition associated to a sleeve gastrectomy in 120 patients.Obesity surgery · 2011Article
- Article
- Changes in neurohormonal gut peptides following bariatric surgery.International journal of obesity (2005) · 2011Review
- Laparoscopic sleeve gastrectomy with ileal interposition (SGIT): a modified duodenal switch for resolution of type 2 diabetes mellitus in lesser obese patients (BMI < 35).World journal of surgery · 2011Article
- Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities.American journal of physiology. Gastrointestinal and liver physiology · 2010Article
- Animal models in bariatric surgery--a review of the surgical techniques and postsurgical physiology.Obesity surgery · 2010Review
- [Indications and principles of metabolic surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2010Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBariatric surgery has evolved into multiple forms in the last decades, combining food restriction and malabsorption. The aim of this study was to develop a new technique based on food restriction and early stimulation of the distal gut, thus maintaining the alimentary tract continuity.
methodsThirty-two Yorkshire pigs, weight 22.2 +/- 5.4 kg (mean +/- SD) were randomly assigned to four laparoscopic procedures: ileal transposition (IT, n = 8); sleeve gastrectomy with ileal transposition (SGIT, n = 8); Roux-en-Y gastric bypass (GBP, n = 8); sham operation (SHAM, n = 8). Firing 45-mm linear staplers over a 60-F bougie, resecting the greater curvature and fundus, constituted a sleeve gastrectomy. Ileal transposition was performed by isolating a 100-cm ileal segment proximal to the ileocecal valve and by dividing the proximal jejunum 15 cm distal to the ligament of Treitz and performing re-anastomosis. Gastric bypass consisted of creating a proximal gastric pouch and a 300 cm alimentary limb. Sham operation was performed by bowel transections and re-anastomosis in the ileum and proximal jejunum together with gastrotomy and closure. Animals were evaluated weekly for weight increase and food intake. We performed a logistic regression analysis to compare weight progression curves, and analysis of variance (ANOVA) and Bonferroni (Dunn) tests to detect differences in weight and food intake.
resultsWe observed significant differences in mean weight after 18 weeks between SGIT (30.9 +/- 13.4 kg) and SHAM (72.5 +/- 10.7 kg) (p = 0.0002), and GBP (28.6 +/- 2.5 kg) and SHAM (p = 0.0001), and IT (56.1 +/- 13.4 kg) and SHAM (p = 0.0081). No differences were observed between RYGB and SGIT. We also observed significant differences in food intake (grams per day) in the third month between SGIT (1668 +/- 677 g) versus SHAM (3252 +/- 476 g) (p = 0.0006), and GBP (2011 +/- 565 g) versus SHAM (p = 0.039). No differences were observed in food intake between SGIT and GBP.
conclusionSGIT proved to be as effective in the short term as GBP on weight progression with no bypass of the proximal gut.
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