ArticleThe Ulster medical journal2008
Sex-differences in lung cancer cell-types? An epidemiologic study in Ireland.
Article in The Ulster medical journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Sex-Specific Silica Nanoparticle Protein Corona Compositions Exposed to Male and Female BALB/c Mice Plasmas.ACS bio & med chem Au · 2023Article
- Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk.Human molecular genetics · 2022Article
- Role of sex hormones in lung cancer.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- Nanoscale Technologies for Prevention and Treatment of Heart Failure: Challenges and Opportunities.Chemical reviews · 2019Review
- Restoration of CBX7 expression increases the susceptibility of human lung carcinoma cells to irinotecan treatment.Naunyn-Schmiedeberg's archives of pharmacology · 2015Article
- UbcH10 expression provides a useful tool for the prognosis and treatment of non-small cell lung cancer.Journal of cancer research and clinical oncology · 2012Article
- Chapter 7: Description of MISCAN-lung, the Erasmus MC Lung Cancer microsimulation model for evaluating cancer control interventions.Risk analysis : an official publication of the Society for Risk Analysis · 2012Article
- Utility of Image Guided Fine Needle Aspiration Cytology in Intra-Thoracic Lesions with Emphasis on Lung Cancer Detection.Journal of cytologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study assesses the epidemiological pattern of lung cancer cell-types in Ireland, with identification of any underlying gender variations.
methodsLung cancer incidence data, including the major cell-types: squamous-cell-carcinoma (SCC), adenocarcinoma (AC), small-cell-lung-carcinoma (SCLC) and large-cell-carcinoma (LCC) were obtained from the national cancer registry (1994-2000), together with individual characteristics, such as age, gender, smoking status, and the year of diagnosis. Age-standardised incidence rates (ASIR), male-to-female (M: F) rate ratios (RR) of ASIR for SCC and AC, as well as RR of AC: SCC according to smoking status for both sexes, were estimated. Estimated-annual-percent-changes for each of the cell-types were calculated.
resultsAC incidence in females is rising annually (8.5%, p = 0.008) from 1994 to 2000, while SCC is declining (-5.4%, p = 0.01) in males. M: F ratios of ASIR are consistently greater than 'one', but converging recently. RR of AC: SCC is also approaching 'unity' across both sexes, irrespective of the smoking status
conclusionsAn apparent increase in lung AC incidence in females was observed in Ireland that might indicate some local environmental risk factors, in addition to changing smoking habits. The study findings do not support the hypothesis that females in general are at higher risk for lung cancer development, but tobacco and histologic-specific susceptibility cannot be ruled out.
Indexed as
Identifiers
18269115PMC2397001W2165823785What OpenQuestion holds
Registered trials
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