ArticleProceedings of the National Academy of Sciences of the United States of America2008
Extraordinary intraspecific diversity in oyster sperm bindin.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 98 citations in OpenAlex.
- The role of ladderlectin in spermatogenesis and ovarian sperm storage in the black rockfish (Sebastes schlegelii).Communications biology · 2025Article
- F-type lectins: Structural and functional aspects, and potential biomedical applications.BBA advances · 2025Article
- Rapid divergence of a gamete recognition gene promoted macroevolution of Eutheria.Genome biology · 2022Article
- First Insights into the Repertoire of Secretory Lectins in Rotifers.Marine drugs · 2022Article
- Deciphering the Link between Doubly Uniparental Inheritance of mtDNA and Sex Determination in Bivalves: Clues from Comparative Transcriptomics.Genome biology and evolution · 2018Article
- F-Type Lectins: A Highly Diversified Family of Fucose-Binding Proteins with a Unique Sequence Motif and Structural Fold, Involved in Self/Non-Self-Recognition.Frontiers in immunology · 2017Review
- DNA polymorphism and selection at the bindin locus in three Strongylocentrotus sp. (Echinoidea).BMC genetics · 2016Article
- Selection and demographic history shape the molecular evolution of the gamete compatibility protein bindin in Pisaster sea stars.Ecology and evolution · 2014Article
- Mass spectrometry and next-generation sequencing reveal an abundant and rapidly evolving abalone sperm protein.Molecular reproduction and development · 2013Article
- Sea star populations diverge by positive selection at a sperm-egg compatibility locus.Ecology and evolution · 2013Article
- A high load of non-neutral amino-acid polymorphisms explains high protein diversity despite moderate effective population size in a marine bivalve with sweepstakes reproduction.G3 (Bethesda, Md.) · 2013Article
- Assessing the potential for egg chemoattractants to mediate sexual selection in a broadcast spawning marine invertebrate.Proceedings. Biological sciences · 2012Article
- Diversity in recognition of glycans by F-type lectins and galectins: molecular, structural, and biophysical aspects.Annals of the New York Academy of Sciences · 2012Review
- Gametogenesis in the Pacific oyster Crassostrea gigas: a microarrays-based analysis identifies sex and stage specific genes.PloS one · 2012Article
- Selection in the rapid evolution of gamete recognition proteins in marine invertebrates.Cold Spring Harbor perspectives in biology · 2011Review
- Crassostrea angulata bindin gene and the divergence of fucose-binding lectin repeats among three species of Crassostrea.Marine biotechnology (New York, N.Y.) · 2011Article
- Diversity-enhancing selection acts on a female reproductive protease family in four subspecies of Drosophila mojavensis.Genetics · 2011Article
- Proteomic discovery of previously unannotated, rapidly evolving seminal fluid genes in Drosophila.Genome research · 2009Article
- Duplication, selection and gene conversion in a Drosophila mojavensis female reproductive protein family.Genetics · 2009Article
- High affinity interaction between a bivalve C-type lectin and a biantennary complex-type N-glycan revealed by crystallography and microcalorimetry.The Journal of biological chemistry · 2008Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
In free-spawning invertebrates sperm-egg incompatibility is a barrier to mating between species, and divergence of gamete recognition proteins (GRPs) can result in reproductive isolation. Of interest are processes that create reproductive protein diversity within species, because intraspecific variants are potentially involved in mate choice and early speciation. Sperm acrosomes of the Pacific oyster Crassostrea gigas contain the protein bindin that bonds sperm to egg during fertilization. Oyster bindin is a single-copy gene encoding a diversity of protein variants. Oyster bindins have a conserved N-terminal region followed by one to five tandem fucose-binding lectin (F-lectin) domains. These repeats have diversified by positive selection at eight sites clustered on the F-lectin's fucose binding face. Additional bindin variants result from recombination in an intron in each F-lectin repeat. Males also express alternatively spliced bindin cDNAs with one to five repeats, but typically translate only one or two isoforms into protein. Thus, positive selection, alternative splicing, and recombination can create thousands of bindin variants within C. gigas. Models of sexual conflict predict high male diversity when females are diverse and sexual conflict is strong. The amount of intraspecific polymorphism in male GRPs may be a consequence of the relative efficiency of local (molecular recognition) and global (electrical, cortical, and physical) polyspermy blocks that operate during fertilization.
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