Evidence map›Paper›PMID 1826827›Full record

ArticleArchives of virology1991

Expression of the NS1 gene of dengue virus type 2 using vaccinia virus. Dimerisation of the NS1 glycoprotein.

C R Parrish, W S Woo, P J Wright

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In one paragraph

Article in Archives of virology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Optimization of recombinant Zika virus NS1 protein secretion from HEK293 cells.Biotechnology reports (Amsterdam, Netherlands) · 2020
    Article
  3. Review
  4. Super induction of dengue virus NS1 protein in E. coli.Protein expression and purification · 2009
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C R ParrishDepartment of Microbiology, Monash University, Clayton, Victoria, Australia.
W S Woo
P J Wright
Monash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A part of the genome of dengue virus type 2 spanning the coding region from the carboxy terminus of the envelope protein E to the beginning of the NS3 protein was expressed using recombinant vaccinia virus. Additional constructs which contained open reading frames terminating within the NS1 or NS2A genes were also expressed. NS1 dimers were formed by extended NS1 molecules containing 61 amino acids of NS2A. No dimers were detected when NS1 was shortened by 79 amino acids at its carboxy terminus.

Indexed as

Genes, ViralAnimalsBlotting, WesternCapsidCell LineCloning, MolecularDengue VirusGene ExpressionHumansMiceTransfectionVaccinia virusViral Core ProteinsViral Nonstructural ProteinsViral Core ProteinsViral Nonstructural Proteins

Identifiers

PMID1826827
OpenAlexW2319797287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.