Evidence map›Paper›PMID 18267300›Full record

ArticleGenomics, proteomics & bioinformatics2007

U7 snRNAs: a computational survey.

Manja Marz, Axel Mosig, Bärbel M R Stadler, Peter F Stadler

Abstract read
In one paragraph

Article in Genomics, proteomics & bioinformatics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Identification and characterization of histones inNAR genomics and bioinformatics · 2021
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Cajal body function in genome organization and transcriptome diversity.BioEssays : news and reviews in molecular, cellular and developmental biology · 2016
    Review
  10. Nuclear bodies: Built to boost.The Journal of cell biology · 2016
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manja MarzBioinformatics Group, Department of Computer Science, University of Leipzig, Leipzig D-04107, Germany.
Axel Mosig
Bärbel M R Stadler
Peter F Stadler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

U7 small nuclear RNA (snRNA) sequences have been described only for a handful of animal species in the past. Here we describe a computational search for functional U7 snRNA genes throughout vertebrates including the upstream sequence elements characteristic for snRNAs transcribed by polymerase II. Based on the results of this search, we discuss the high variability of U7 snRNAs in both sequence and structure, and report on an attempt to find U7 snRNA sequences in basal deuterostomes and non-drosophilids insect genomes based on a combination of sequence, structure, and promoter features. Due to the extremely short sequence and the high variability in both sequence and structure, no unambiguous candidates were found. These results cast doubt on putative U7 homologs in even more distant organisms that are reported in the most recent release of the Rfam database.

Indexed as

AnimalsBase SequenceDatabases, Nucleic AcidEvolution, MolecularGenomicsHumansMolecular Sequence DataNucleic Acid ConformationRNA, Small NuclearSequence AlignmentSpecies SpecificityVertebratesRNA, Small NuclearU7 small nuclear RNA

Identifiers

PMID18267300
PMCPMC5054213

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.