ReviewInternational journal of clinical practice2008
The triad of erectile dysfunction, hypogonadism and the metabolic syndrome.
Review in International journal of clinical practice, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 105 citations in OpenAlex.
- Observational
- Uncovering the Potential Mechanisms and Effects of Hyperuricemia and its Associated Diseases on Male Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2024Review
- Evaluation of the frequency of metabolic syndrome and assessment of cardiometabolic index among men with erectile dysfunction: a prospective cross-sectional study.Journal of diabetes and metabolic disorders · 2023Article
- Sexual Dysfunctions in Obese Women Before and After Bariatric Surgery.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Androgens and Blood Pressure Control: Sex Differences and Mechanisms.Mayo Clinic proceedings · 2019Review
- Hip Fracture in People with Erectile Dysfunction: A Nationwide Population-Based Cohort Study.PloS one · 2016Article
- Lower urinary tract symptoms improve with testosterone replacement therapy in men with late-onset hypogonadism: 5-year prospective, observational and longitudinal registry study.World journal of urology · 2014Observational
- Chronic high dose intraperitoneal bisphenol A (BPA) induces substantial histological and gene expression alterations in rat penile tissue without impairing erectile function.The journal of sexual medicine · 2013Article
- A survey on relative frequency of metabolic syndrome and testosterone deficiency in men with erectile dysfunction.International urology and nephrology · 2012Article
- Testosterone supplementation in male obese Zucker rats reduces body weight and improves insulin sensitivity but increases blood pressure.Hypertension (Dallas, Tex. : 1979) · 2012Article
- Hypogonadism in the aging male diagnosis, potential benefits, and risks of testosterone replacement therapy.International journal of endocrinology · 2012Article
- Metabolic syndrome, hormone levels, and inflammation in patients with erectile dysfunction.TheScientificWorldJournal · 2012Article
- Sex hormone-binding globulin, but not testosterone, is associated prospectively and independently with incident metabolic syndrome in men: the framingham heart study.Diabetes care · 2011Article
- Metabolic syndrome, androgens, and hypertension.Current hypertension reports · 2011Review
- Androgens and hypertension: role in both males and females?Hypertension (Dallas, Tex. : 1979) · 2011Article
- Testosterone and the metabolic syndrome.Therapeutic advances in endocrinology and metabolism · 2010Article
- Androgens and male aging: Current evidence of safety and efficacy.Asian journal of andrology · 2010Review
- Treatment of erectile dysfunction in the obese type 2 diabetic ZDF rat with adipose tissue-derived stem cells.The journal of sexual medicine · 2010Article
- Clinical review: Prevalence and incidence of endocrine and metabolic disorders in the United States: a comprehensive review.The Journal of clinical endocrinology and metabolism · 2009Review
- Reversal of voltage-dependent erectile responses in the Zucker obese-diabetic rat by rosuvastatin-altered RhoA/Rho-kinase signaling.The journal of sexual medicine · 2009Article
Corrections and comments
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Authors and funding
10 authors at 9 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo identify the relationship of erectile dysfunction, hypogonadism and the metabolic syndrome in the context of men's health.
methodsAn Expert Panel Meeting was held in December 2006 in Vienna, Austria. In addition a comprehensive literature search was conducted.
resultsMen have a higher incidence of cardiovascular events than women of similar ages which has led to the belief that testosterone is a risk factor for cardiovascular disease in men. The latter hypothesis is no longer tenable. On the contrary, low testosterone levels are associated with (visceral) obesity, the metabolic syndrome, diabetes mellitus, cardiovascular disease and erectile dysfunction (ED). Testosterone therapy does not lead to an increased incidence of cardiovascular disease or events such as myocardial infarction, stroke or angina. Until recently (visceral) obesity, the metabolic syndrome, diabetes mellitus, cardiovascular disease and ED were viewed as more or less independent entities affecting the ageing male. It was not recognised that hypogonadism is a common denominator. With a more integrative approach to the health situation of middle-aged and elderly men, these conditions appear closely interrelated in their manifestations, hypothetically in their aetiology, diagnostic strategy and also their treatment.
conclusionImproving sexual health is a portal to identify health hazards and improving men's health. Appropriate diagnosis and medical work up of men presenting with sexual symptoms may have the benefit of the diagnosing and treating other important conditions, such as obesity, diabetes, hypertension and hyperlipidaemia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.