Evidence map›Paper›PMID 18263974›Full record

ReviewJournal of applied genetics2008

"Treasure your exceptions": recent advances in molecular genetics of glomerular disease.

Andrzej Ciechanowicz, Andrzej Brodkiewicz, Agnieszka Bińczak-Kuleta, Miłosz Parczewski, Stanłisaw Czekalski

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of applied genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrzej CiechanowiczDepartment of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University, Powstańcow Wielkopolskich 72, 70-111 Szczecin, Poland. aciech@sci.pam.szczecin.pl
Andrzej Brodkiewicz
Agnieszka Bińczak-Kuleta
Miłosz Parczewski
Stanłisaw Czekalski

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The glomerular filtration barrier consists of endothelial cells, the glomerular basement membrane, and podocytes. The membrane is a highly crosslinked macromolecular meshwork composed of specific extracellular matrix proteins. The adjacent foot processes of podocytes are bridged along their basolateral surfaces by a slit diaphragm (a porous filter structure of nephrin molecules). Recent discoveries of mutations in the range of genes encoding proteins involved in the structure or function of the glomerular filtration barrier have provided new insights into mechanisms of glomerular diseases. In this review, we summarize recent progress in the elucidation of the genetic basis of some glomerulopathies in humans.

Indexed as

Molecular BiologyAnimalsHumansKidney DiseasesKidney Glomerulus

Identifiers

PMID18263974

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.