ReviewNucleic acids research2008
Spliceosomal introns as tools for genomic and evolutionary analysis.
Review in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Complete Chloroplast Genome Sequence and Phylogenetic Analysis of the Tibetan Medicinal PlantGenes · 2025Article
- Molecular analyses of the tubby-like protein gene family and their response to salt and high temperature in the foxtail millet (Setaria italica).Functional & integrative genomics · 2024Article
- MIPs: multi-locus intron polymorphisms in species identification and population genomics.Scientific reports · 2024Article
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- Article
- Transcriptome-wide identification of walnut PP2C family genes in response to external stimulus.BMC genomics · 2022Article
- ExOrthist: a tool to infer exon orthologies at any evolutionary distance.Genome biology · 2021Article
- Conservative route to genome compaction in a miniature annelid.Nature ecology & evolution · 2021Article
- Contribution of introns to the species diversity associated with the apicomplexan parasite, Neospora caninum.Parasitology research · 2020Article
- The complex evolutionary history of sulfoxide synthase in ovothiol biosynthesis.Proceedings. Biological sciences · 2019Article
- The evolutionary landscape of the Rab family in chordates.Cellular and molecular life sciences : CMLS · 2019Article
- Evolutionary recruitment of flexible Esrp-dependent splicing programs into diverse embryonic morphogenetic processes.Nature communications · 2017Article
- Architecture and Distribution of Introns in Core Genes of FourG3 (Bethesda, Md.) · 2017Article
- Tracing the Evolutionary History of the CAP Superfamily of Proteins Using Amino Acid Sequence Homology and Conservation of Splice Sites.Journal of molecular evolution · 2017Article
- Myosin repertoire expansion coincides with eukaryotic diversification in the Mesoproterozoic era.BMC evolutionary biology · 2017Article
- The Tetraspanin-Associated Uroplakins Family (UPK2/3) Is Evolutionarily Related to PTPRQ, a Phosphotyrosine Phosphatase Receptor.PloS one · 2017Article
- Identification and characterization of the GhHsp20 gene family in Gossypium hirsutum.Scientific reports · 2016Article
- Article
- Origin of spliceosomal introns and alternative splicing.Cold Spring Harbor perspectives in biology · 2014Article
- Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Over the past 5 years, the availability of dozens of whole genomic sequences from a wide variety of eukaryotic lineages has revealed a very large amount of information about the dynamics of intron loss and gain through eukaryotic history, as well as the evolution of intron sequences. Implicit in these advances is a great deal of information about the structure and evolution of surrounding sequences. Here, we review the wealth of ways in which structures of spliceosomal introns as well as their conservation and change through evolution may be harnessed for evolutionary and genomic analysis. First, we discuss uses of intron length distributions and positions in sequence assembly and annotation, and for improving alignment of homologous regions. Second, we review uses of introns in evolutionary studies, including the utility of introns as indicators of rates of sequence evolution, for inferences about molecular evolution, as signatures of orthology and paralogy, and for estimating rates of nucleotide substitution. We conclude with a discussion of phylogenetic methods utilizing intron sequences and positions.
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