ArticleAnnals of epidemiology2008
Characteristics related to the maternal intrauterine environment and risk of epithelial ovarian cancer.
Article in Annals of epidemiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Association between vitamin BFrontiers in pediatrics · 2025Article
- Intrauterine factors and risk of nonepithelial ovarian cancers.Gynecologic oncology · 2014Article
- Body size in early life and risk of epithelial ovarian cancer: results from the Nurses' Health Studies.British journal of cancer · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
purposeIn contrast to other hormonally mediated cancers such as those of the breast, prostate, and testes, almost no data are available regarding the relation of prenatal characteristics and exposures to subsequent ovarian carcinogenesis. In a population-based study of 812 women ages 35-74 years with epithelial ovarian cancer diagnosed in Washington State from 2002 to 2005 and 1313 controls, we assessed the relation of such factors to disease risk.
methodsInformation was collected through in-person interviews and logistic regression was used to calculate odds ratios and 95% confidence intervals.
resultsOverall, we noted little evidence that prenatal or birth characteristics including birth weight, birth order, maternal age, or in utero exposure to cigarette smoking were associated with risk of epithelial ovarian cancer in adulthood. Among women younger than 55 years of age, risk was reduced among those whose weight at birth was < 5.5 pounds (odds ratio and 95% confidence interval 0.54, 0.31-0.94) relative to those with birth weight 5.5-9 pounds.
conclusionsIn this study, birth weight was associated with risk of epithelial ovarian cancer only among women younger than 55 years of age. Prenatal influences might be expected to more substantially influence cancer risk at younger ages. Other reports examining associations of ovarian cancer risk with birth weight or other prenatal characteristics are few and have not examined risk separately according to age at diagnosis, suggesting that additional studies may prove useful.
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Registered trials
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