ReviewWorld journal of surgery2008
Recent advances in molecular mechanisms of abdominal aortic aneurysm formation.
Review in World journal of surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 60 citations in OpenAlex.
- Apolipoprotein E Deficiency Produces an Inflammatory Abdominal Aortic Aneurysm in a Rat Calcium Chloride-Induced Model.The Journal of surgical research · 2025Article
- Thoracic aortic aneurysm combined with intracranial vascular abnormalities caused by dual mutations inFrontiers in genetics · 2025Article
- The active mechanical characteristics of arterial smooth muscle during aneurysm remodeling.Frontiers in bioengineering and biotechnology · 2025Article
- Peptide Amphiphile Supramolecular Nanofibers Designed to Target Abdominal Aortic Aneurysms.ACS nano · 2022Article
- Genome-Wide Identification of Immune-Related Alternative Splicing and Splicing Regulators Involved in Abdominal Aortic Aneurysm.Frontiers in genetics · 2022Article
- Identification of a Plasma Microrna Signature as Biomarker of Subaneurysmal Aortic Dilation in Patients with High Cardiovascular Risk.Journal of clinical medicine · 2020Article
- Abnormal Flow Dynamics Result in Low Wall Shear Stress and High Oscillatory Shear Index in Abdominal Aortic Dilatation: Initial in vivo Assessment with 4D-flow MRI.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2020Article
- Article
- Nanoparticulate delivery of agents for induced elastogenesis in three-dimensional collagenous matrices.Journal of tissue engineering and regenerative medicine · 2016Article
- Androgen receptor (AR) in cardiovascular diseases.The Journal of endocrinology · 2016Review
- Identification and characterization of CD4(+)AT2(+) T lymphocyte population in human thoracic aortic aneurysm.American journal of translational research · 2015Article
- Atrial endothelial impairment through Toll-like receptor 4 signaling causes atrial thrombogenesis.Heart and vessels · 2014Article
- Establishment of a new murine elastase-induced aneurysm model combined with transplantation.PloS one · 2014Article
- Abdominal aortic aneurysms targeted by functionalized polysaccharide microparticles: a new tool for SPECT imaging.Theranostics · 2014Article
- Cathepsins: a new culprit behind abdominal aortic aneurysm.Regenerative medicine research · 2013Review
- Inhibition of rho-kinase by fasudil suppresses formation and progression of experimental abdominal aortic aneurysms.PloS one · 2013Article
- Cysteine protease cathepsins and matrix metalloproteinases in the development of abdominal aortic aneurysms.Future cardiology · 2013Review
- Article
- Diagnostic and therapeutic strategies for small abdominal aortic aneurysms.Nature reviews. Cardiology · 2011Review
- Animal models of cardiovascular diseases.Journal of biomedicine & biotechnology · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Abdominal aortic aneurysm (AAA) is an increasingly common clinical condition with fatal implications. It is associated with advanced age, male gender, cigarette smoking, atherosclerosis, hypertension, and genetic predisposition. Although significant evidence has emerged in the last decade, the molecular mechanisms of AAA formation remain poorly understood. Currently, the treatment for AAA remains primarily surgical with the lone innovation of endovascular therapy. With advances in the human genome, understanding precisely which molecules and genes mediate AAA development and blocking their activity at the molecular level could lead to important new discoveries and therapies. This review summarizes recent updates in molecular mechanisms of AAA formation, including animal models, autoimmune components, infection, key molecules and cytokines, mechanical forces, genetics, and pharmacotherapy. This review will be helpful to those who want to recognize the newest endeavors within the field and identify possible lines of investigation in AAA.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.