ReviewPediatric nephrology (Berlin, Germany)2008
Treatment of autosomal dominant polycystic kidney disease (ADPKD): the new horizon for children with ADPKD.
Review in Pediatric nephrology (Berlin, Germany), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- Polycystic Kidney Disease-Related Disease Burden in Adolescents With Autosomal Dominant Polycystic Kidney Disease: An International Qualitative Study.Kidney medicine · 2022Article
- Aquatic models of human ciliary diseases.Genesis (New York, N.Y. : 2000) · 2021Review
- The fertility willingness and acceptability of preimplantation genetic testing in Chinese patients with autosomal dominant polycystic kidney disease.BMC nephrology · 2020Article
- ADPedKD: A Global Online Platform on the Management of Children With ADPKD.Kidney international reports · 2019Article
- Antenatally Diagnosed ADPKD.Kidney international reports · 2018Article
- Understanding the physical and emotional impact of early-stage ADPKD: experiences and perspectives of patients and physicians.Clinical kidney journal · 2015Article
- From bone abnormalities to mineral metabolism dysregulation in autosomal dominant polycystic kidney disease.Pediatric nephrology (Berlin, Germany) · 2013Review
- Looking at the (w)hole: magnet resonance imaging in polycystic kidney disease.Pediatric nephrology (Berlin, Germany) · 2013Review
- Growth of arachnoid cysts in patients with autosomal dominant polycystic kidney disease: serial imaging and clinical relevance.Clinical kidney journal · 2012Article
- Early renal abnormalities in children with postnatally diagnosed autosomal dominant polycystic kidney disease.Pediatric nephrology (Berlin, Germany) · 2012Article
- Diagnosis and management of childhood polycystic kidney disease.Pediatric nephrology (Berlin, Germany) · 2011Review
- Similar renal outcomes in children with ADPKD diagnosed by screening or presenting with symptoms.Pediatric nephrology (Berlin, Germany) · 2010Article
- The role of transient receptor potential channels in kidney disease.Nature reviews. Nephrology · 2009Review
- Genotype-phenotype correlation in children with autosomal dominant polycystic kidney disease.Pediatric nephrology (Berlin, Germany) · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polycystic kidney disease (PKD) is the most common inherited renal disorder. Patients with PKD remain clinically asymptomatic for decades, while significant anatomic and physiologic systemic changes take place. Sequencing of the responsible genes and identification of their protein products have significantly expanded our understanding of the pathophysiology of PKD. The molecular basis for cystogenesis is being unraveled, leading to new targets for therapy and giving hope to millions of people suffering from PKD. This has direct implications for children with PKD with regard to screening for the disease and identification of high-risk individuals. In this article we provide a review of the clinical manifestations in children with autosomal dominant polycystic kidney disease (ADPKD), the genetic and molecular basis for the disease, and a concise review of potential therapies being evaluated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.