Evidence map›Paper›PMID 18258110›Full record

ArticleEmerging infectious diseases2008

Dissemination of clonally related Escherichia coli strains expressing extended-spectrum beta-lactamase CTX-M-15.

Teresa M Coque, Angela Novais, Alessandra Carattoli, Laurent Poirel, Johann Pitout, Luísa Peixe, Fernando Baquero, Rafael Cantón, Patrice Nordmann

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 303 papers.

0numbers the graph read from it
0cells of the map it votes in
303citing papers in PubMed
19.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

303 citing papers in PubMed, 694 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Fluoroquinolone resistantFrontiers in microbiology · 2026
    Article
  8. Article
  9. Review
  10. Phylogroup Homeostasis ofMicroorganisms · 2025
    Article
  11. Molecular analysis of AmpC-producing Escherichia coli isolated from pediatric patients.Journal of the Pediatric Infectious Diseases Society · 2025
    Article
  12. Article
  13. Emergence of Carbapenem-Resistant UropathogenicPathogens (Basel, Switzerland) · 2024
    Article
  14. Article
  15. A NovelAntibiotics (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Molecular characterization of Escherichia coli producing extended-spectrum β-lactamase CTX-M-14 and CTX-M-28 in Mexico.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  20. Article

243 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Teresa M CoqueHospital Universitario Ramón y Cajal, Madrid, Spain. mcoque.hrc@salud.madrid.org
Angela Novais
Alessandra Carattoli
Laurent Poirel
Johann Pitout
Luísa Peixe
Fernando Baquero
Rafael Cantón
Patrice Nordmann
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESBicêtre Hospital · FRHospital Universitario Ramón y Cajal · ESIstituto Superiore di Sanità · ITUniversidade do Porto · PTUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We analyzed 43 CTX-M-15-producing Escherichia coli isolates and 6 plasmids encoding the blaCTX-M-15 gene from Canada, India, Kuwait, France, Switzerland, Portugal, and Spain. Most isolates belonged to phylogroups B2 (50%) and D (25%). An EC-B2 strain of clonal complex sequence type (ST) 131 was detected in all countries; other B2 isolates corresponded to ST28, ST405, ST354, and ST695 from specific areas. EC-D strains were clonally unrelated but isolates from 3 countries belonged to ST405. All CTX-M-15 plasmids corresponded to IncFII group with overrepresentation of 3 HpaI-digested plasmid DNA profiles (A, B and C; 85-120kb, similarity > or =70%). Plasmid A was detected in EC-B2 strains (ST131, ST354, or ST405), plasmid C was detected in B2 and D strains, and plasmid B was confined to worldwide-disseminated ST131. Most plasmids contained blaOXA-1, aac(6')-Ib-cr, and blaTEM-1. Worldwide dissemination of CTX-M-15 seems to be determined by clonal complexes ST131 and ST405 and multidrug-resistant IncFII plasmids.

Indexed as

beta-Lactamasesbeta-Lactam ResistanceCanadaDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsEuropeHumansIndiaKuwaitPlasmidsbeta-lactamase CTX-M-15beta-LactamasesEscherichia coli Proteins

Identifiers

PMID18258110
PMCPMC2600198
OpenAlexW2027944446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.