ArticleEmerging infectious diseases2008
Epidemiology of Haemophilus influenzae serotype a, North American Arctic, 2000-2005.
Article in Emerging infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- A decade of research in Inuit children, youth, and maternal health in Canada: areas of concentrations and scarcities.International journal of circumpolar health · 2012Pooled it
- Epidemiology of invasiveInternational journal of circumpolar health · 2022Article
- Structural Characterization ofPathogens (Basel, Switzerland) · 2021Article
- Invasive bacterial diseases in northern Canada, 1999 to 2018.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021Article
- Racial Disparities in Invasive Haemophilus influenzae Disease-United States, 2008-2017.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Epidemiology of Invasive Haemophilus influenzae Serotype a Disease-United States, 2008-2017.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Long Term Impact of Conjugate Vaccines onMicroorganisms · 2021Review
- Molecular diagnostic assays for the detection of common bacterial meningitis pathogens: A narrative review.EBioMedicine · 2021Review
- Current Epidemiology and Trends in Invasive Haemophilus influenzae Disease-United States, 2009-2015.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Invasive Haemophilus influenzae Serotype a Infection in Children: Clinical Description of an Emerging Pathogen-Alaska, 2002-2014.The Pediatric infectious disease journal · 2018Article
- RNA gene profile variation in peripheral blood mononuclear cells from rhesus macaques immunized with Hib conjugate vaccine, Hib capsular polysaccharide and TT carrier protein.BMC immunology · 2018Article
- The emergingCanada communicable disease report = Releve des maladies transmissibles au Canada · 2017Article
- Connecting remote populations to public health: the case for a digital immunisation information system in Nunavut.International journal of circumpolar health · 2017Article
- Article
- Invasive Bacterial Diseases in Northern Canada, 2006-2013.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2016Article
- Laboratory characterization of invasive Haemophilus influenzae isolates from Nunavut, Canada, 2000-2012.International journal of circumpolar health · 2016Article
- Hib Vaccines: Past, Present, and Future Perspectives.Journal of immunology research · 2016Review
- Simulating Immune Interference on the Effect of a Bivalent Glycoconjugate Vaccine against Haemophilus influenzae Serotypes "a" and "b".The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2016Article
- Invasive Disease Caused by Nontypeable Haemophilus influenzae.Emerging infectious diseases · 2015Article
- Evaluation of Haemophilus influenzae type b carrier status among children 10 years after the introduction of Hib vaccine in Brazil.Memorias do Instituto Oswaldo Cruz · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Before the introduction of Haemophilus influenzae type b (Hib) conjugate vaccines, rates of invasive H. influenzae disease among indigenous people of the North American Arctic were among the highest in the world. Routine vaccination reduced rates to low levels; however, serotype replacement with non-type b strains may result in a reemergence of invasive disease in children. We reviewed population-based data on invasive H. influenzae in Alaska and northern Canada from 2000-2005; 138 cases were reported. Among 88 typeable isolates, 42 (48%) were H. influenzae type a (Hia); 35 (83%) occurred in indigenous peoples. Among Hia patients, median age was 1.1 years; 62% were male; 1 adult died. Common clinical manifestations included meningitis, pneumonia, and septic arthritis. Overall annual incidence was 0.9 cases per 100,000 population. Incidence among indigenous children <2 years of age in Alaska and northern Canada was 21 and 102, respectively. Serotype a is now the most common H. influenzae serotype in the North American Arctic; the highest rates are among indigenous children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.