Evidence map›Paper›PMID 18258055›Full record

ArticleEmerging infectious diseases2007

Antimicrobial drug resistance in Singapore hospitals.

Li-Yang Hsu, Thean-Yen Tan, Roland Jureen, Tse-Hsien Koh, Prabha Krishnan, Raymond Tzer-Pin Lin, Nancy Wen-Sin Tee, Paul Ananth Tambyah

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02134106 (Multi-center, Open-label Randomized Controlled Trial on the Efficacy of Combination Antibiotic Therapy for Serious Infections Caused by Extensively Drug-resistant Gram-negative Bacteria), which is not on this map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02134106 phase2 / phase3withdrawnnot on this mapstarted 2015, after this paper: background citation

Multi-center, Open-label Randomized Controlled Trial on the Efficacy of Combination Antibiotic Therapy for Serious Infections Caused by Extensively Drug-resistant Gram-negative Bacteria (XDR-GNB)

TypeinterventionalSponsorTan Tock Seng HospitalRan2015 to 2015Enrolled0ConditionsBacteremia, Healthcare-associated Pneumonia, Ventilator-associated PneumoniaArmsPolymyxin B, Polymyxin B + Doripenem
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 99 citations in OpenAlex.

  1. Trial
  2. Skin and soft tissue infections in primary care.Singapore medical journal · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Diversity and Dissemination of Methicillin-ResistantTropical medicine and infectious disease · 2022
    Review
  7. Review
  8. Article
  9. Article
  10. Methicillin-resistantBMJ case reports · 2021
    Article
  11. Occurrence and Antimicrobial Resistance Traits ofInternational journal of environmental research and public health · 2020
    Article
  12. Article
  13. Study of Antibiotic Sensitivity and Resistance Pattern of Bacterial Isolates in Intensive Care Unit Setup of a Tertiary Care Hospital.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019
    Article
  14. Review
  15. Article
  16. Environmental colonization and onward clonal transmission of carbapenem-resistantAntimicrobial resistance and infection control · 2018
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Li-Yang HsuDepartment of Medicine, National University of Singapore, Singapore. liyang_hsu@yahoo.com
Thean-Yen Tan
Roland Jureen
Tse-Hsien Koh
Prabha Krishnan
Raymond Tzer-Pin Lin
Nancy Wen-Sin Tee
Paul Ananth Tambyah
National University of Singapore · SGAlexandra Hospital · SGKK Women's and Children's Hospital · SGSingapore General Hospital · SGTan Tock Seng Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new national antimicrobial resistance surveillance program in Singapore public hospitals that uses WHONET detected high levels of methicillin resistance among Staphylococcus aureus (35.3%), carbapenem resistance among Acinetobacter spp. (49.6%), and third-generation cephalosporin resistance among Klebsiella pneumoniae (35.9%) hospital isolates in 2006. Antimicrobial drug resistance is a major problem in Singapore.

Indexed as

HospitalsAnti-Bacterial AgentsBacteriaDrug Resistance, Multiple, BacterialHumansSingaporeAnti-Bacterial Agents

Identifiers

PMID18258055
PMCPMC2876746
OpenAlexW2036206262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.