ArticleEmerging infectious diseases2007
Antigenic diversity of human sapoviruses.
Article in Emerging infectious diseases, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Charting the Impact of Maternal Antibodies and Repeat Exposures on Sapovirus Immunity in Early Childhood From a Nicaraguan Birth Cohort.The Journal of infectious diseases · 2025Article
- Propagating and banking genetically diverse human sapovirus strains using a human duodenal cell line: investigating antigenic differences between strains.Journal of virology · 2024Article
- Metagenomic Detection and Genetic Characterization of Human Sapoviruses among Children with Acute Flaccid Paralysis in Nigeria.Pathogens (Basel, Switzerland) · 2024Article
- High-resolution melting analysis for simultaneous detection and discrimination between wild-type and vaccine strains of feline calicivirus.The veterinary quarterly · 2023Article
- Timing and genotype distribution of symptomatic and asymptomatic sapovirus infections and re-infections in a Nicaraguan birth cohort.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2023Article
- Article
- High Genetic Diversity of Porcine Sapovirus From Diarrheic Piglets in Yunnan Province, China.Frontiers in veterinary science · 2022Article
- Serological Humoral Immunity Following Natural Infection of Children with High Burden Gastrointestinal Viruses.Viruses · 2021Review
- Molecular Epidemiology of Human Sapovirus among Children with Acute Gastroenteritis in Western Canada.Journal of clinical microbiology · 2021Article
- Occurrence of Human Enteric Viruses in Water Sources and Shellfish: A Focus on Africa.Food and environmental virology · 2021Review
- Sapovirus: an emerging cause of childhood diarrhea.Current opinion in infectious diseases · 2020Review
- Porcine sapoviruses: Pathogenesis, epidemiology, genetic diversity, and diagnosis.Virus research · 2020Review
- Review
- Etiological Role and Repeated Infections of Sapovirus among Children Aged Less than 2 Years in a Cohort Study in a Peri-urban Community of Peru.Journal of clinical microbiology · 2016Article
- Antigenic and Cryo-Electron Microscopy Structure Analysis of a Chimeric Sapovirus Capsid.Journal of virology · 2015Article
- Comprehensive review of human sapoviruses.Clinical microbiology reviews · 2015Review
- Prevalence of porcine noroviruses, molecular characterization of emerging porcine sapoviruses from finisher swine in the United States, and unified classification scheme for sapoviruses.Journal of clinical microbiology · 2013Article
- Sapovirus in adults in rehabilitation center, upper Austria.Emerging infectious diseases · 2010Article
- Molecular characterization and phylogenetic analysis of the complete genome of a porcine sapovirus from Chinese swine.Virology journal · 2009Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sapovirus (SaV) is a causative agent of gastroenteritis. On the basis of capsid protein (VP1) nucleotide sequences, SaV can be divided into 5 genogroups (GI-GV), of which the GI, GII, GIV, and GV strains infect humans. SaV is uncultivable, but expression of recombinant VP1 in insect cells results in formation of viruslike particles (VLPs) that are antigenically similar to native SaV. In this study, we newly expressed SaV GII and GIV VLPs to compare genetic and antigenic relationships among all human SaV genogroups. Hyperimmune antiserum samples against VLPs reacted strongly with homologous VLPs. However, several antiserum samples weakly cross-reacted against heterologous VLPs in an antibody ELISA. Conversely, an antigen ELISA showed that VLPs of SaV in all human genogroups were antigenically distinct. These findings indicate a likely correspondence between SaV antigenicity and VP1 genogrouping and genotyping.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.