ArticleOsteopathic medicine and primary care2008
OTC analgesics and drug interactions: clinical implications.
Article in Osteopathic medicine and primary care, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 48 citations in OpenAlex.
- Exploring Potential Drug-Drug Interactions: A Cross-Sectional Study of 1 Million e-Prescriptions Across Medical Specialties in Shiraz, Iran (2021-2024).Iranian journal of medical sciences · 2026Article
- Use of non-prescription analgesic medications and survival among Black women with ovarian cancer.British journal of cancer · 2026Article
- Digital Therapeutics (DTx) Expand Multimodal Treatment Options for Chronic Low Back Pain: The Nexus of Precision Medicine, Patient Education, and Public Health.Healthcare (Basel, Switzerland) · 2023Article
- The Use of Psychoactive Substances in Germany.Deutsches Arzteblatt international · 2022Article
- Abuse of Non-opioid Analgesics in Germany: Prevalence and Associations Among Self-Medicated Users.Frontiers in psychiatry · 2022Article
- Not so Goody's powder.BMJ case reports · 2021Article
- Over-the-counter analgesic powder use in patients presenting with intracerebral hemorrhage: A case series.Medicine · 2018Article
- Review
- Patient-perceived barriers and facilitators to the implementation of a medication review in primary care: a qualitative thematic analysis.BMC family practice · 2018Article
- Prevalence, trends, patterns and associations of analgesic use in Germany.BMC pharmacology & toxicology · 2015Article
- Safety issues of current analgesics: an update.Clujul medical (1957) · 2015Review
- Article
- Cooperation between community pharmacists and general practitioners in eastern Germany: attitudes and needs.International journal of clinical pharmacy · 2013Article
- Ibuprofen: pharmacology, efficacy and safety.Inflammopharmacology · 2009Review
- Osteopathic Medicine and Primary Care looks forward to 2009.Osteopathic medicine and primary care · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The risk of drug interactions with concurrent use of multiple medications is a clinically relevant issue. Many patients are unaware that over-the-counter (OTC) analgesics can cause potentially serious adverse effects when used in combination with other common medications such as anticoagulants, corticosteroids, or antihypertensive agents. Of particular significance is the increased risk of upper abdominal gastrointestinal adverse events in patients who take traditional nonsteroidal anti-inflammatory drugs (NSAIDs). This risk is dose dependent and further increased in patients who take more than one NSAID or use NSAIDs in combination with certain other medications. Some NSAIDs may also mitigate the antiplatelet benefits of aspirin and may increase blood pressure in patients with hypertension. Clinicians should be aware of potential drug interactions with OTC analgesics when prescribing new medications. Additionally, patients should be properly counseled on the appropriate and safe use of OTC analgesics.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.