Evidence map›Paper›PMID 18256679›Full record

ReviewNature clinical practice. Neurology2008

Training and exercise to drive poststroke recovery.

Bruce H Dobkin

Registry-linked trialAbstract readReview
In one paragraph

Review in Nature clinical practice. Neurology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02759328 (Clinical Feasibility of the Xbox Kinect™ Training for Stroke Rehabilitation), which is not on this map. Cited by 65 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 2 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02759328 nacompletednot on this mapstarted 2012, after this paper: background citation

Clinical Feasibility of the Xbox Kinect™ Training for Stroke Rehabilitation: a Single Blind Randomized Controlled Pilot Study

TypeinterventionalSponsorAnkara UniversityRan2012 to 2014Enrolled20ConditionsStrokeArmsXbox Kinect™ training, Conventional rehabilitation
3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 2 syntheses or guidelines pooled it, 191 citations in OpenAlex.

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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Bruce H DobkinUniversity of California, Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095, USA. bdobkin@mednet.ucla.edu
University of California, Los Angeles · US

Funding

Locomotor Experience Applied Post-Stroke (LEAPS)R01NS050506 · NINDS · UNIVERSITY OF FLORIDA · PI DUNCAN, PAMELA W. · 2005 to 2009
$13.3M
WESTERN REHABILITATION RESEARCH NETWORKR24HD039629 · NICHD · UNIVERSITY OF WASHINGTON · PI ANDERSON, MARJORIE E · 2000 to 2004
$4.8M
fMRI Predictor Model for Stroke Locomotor RehabilitationR01HD046740 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DOBKIN, BRUCE H · 2005 to 2008
$1.6M
NRSA IN NEUROLOGICAL REHABILITATIONT32NS007479 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DOBKIN, BRUCE HARVEY · 1999 to 2003
$792k
NICHD NIH HHS R01 HD046740NICHD NIH HHS R24 HD039629NINDS NIH HHS R01 NS050506NINDS NIH HHS T32 NS007479
6 · The paper itself

Abstract

To make practical recommendations regarding therapeutic strategies for the rehabilitation of patients with hemiparetic stroke, it is important to have a general understanding of the fundamental mechanisms underlying the neuroplasticity that is induced by skills training and by exercise programs designed to increase muscle strength and cardiovascular fitness. Recent clinical trials have provided insights into methods that promote adaptations within the nervous system that correlate with improved walking and upper extremity function, and that can be instigated at any time after stroke onset. Data obtained to date indicate that patients who have mild to moderate levels of impairment and disability can benefit from interventions that depend on repetitive task-oriented practice at the intensity and duration necessary to reach a plateau in a reacquired skill. Studies are underway to lessen the consequences of more-severe motor deficits by drawing on medications that augment plasticity, biological interventions that promote neural repair, and strategies that employ electrical stimulation and robotics.

Indexed as

Exercise TherapyStroke RehabilitationActivities of Daily LivingAnimalsHumansRecovery of FunctionStrokeTime Factors

Identifiers

PMID18256679
PMCPMC4099052
OpenAlexW2077708730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.