ArticleThe Journal of allergy and clinical immunology2008
Exposure to multiple indoor allergens in US homes and its relationship to asthma.
Article in The Journal of allergy and clinical immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
91 citing papers in PubMed, 220 citations in OpenAlex.
- Efficacy of indoor air purification in the treatment of Artemisia pollen-allergic rhinitis: A randomised, double-blind, clinical controlled trial.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2020Trial
- Validation of a novel sampling technology for airborne allergens in low-income urban homes.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2018Trial
- Effects of Symptom Perception Interventions on Trigger Identification and Quality of Life in Children with Asthma.Pulmonary medicine · 2015Trial
- A novel ambient air sampler for detection of allergens and endotoxin.The journal of allergy and clinical immunology. Global · 2026Article
- Associations between reservoir bedroom dust allergen levels and sleep symptoms in school-age children.Sleep health · 2026Article
- Sensitization to Dog Dander Allergen Can f 1 is Associated with Asthma Symptom Severity and Exacerbations in a Singapore-Malaysia Cohort.Journal of asthma and allergy · 2026Article
- Indoor allergens and endotoxins in relation to cockroach infestations in low-income urban homes.The journal of allergy and clinical immunology. Global · 2026Article
- Emerging molecular and environmental biomarkers of shrimp allergy in African Americans in the US.Frontiers in allergy · 2026Review
- Furry Animal Allergy: Lipocalins, Serum Albumins, and Secretoglobins-Cross-Reactivity, Diagnosis, and Management Strategies.Clinical reviews in allergy & immunology · 2025Review
- Effects of aging and cleaning on bed bug (Hemiptera: Cimicidae)-derived histamine.Journal of medical entomology · 2025Article
- Associations between in-home environmental exposures and lung function in a safety net population of children with asthma using electronic health records and geospatial data.Annals of epidemiology · 2025Article
- Indoor allergen exposure in relation to sleep health among US adults.The journal of allergy and clinical immunology. Global · 2025Article
- Depletion of eosinophils during sensitization but not challenge phase in mice blocks the development of food allergy early in life.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Developmental air pollution exposure augments airway hyperreactivity, alters transcriptome, and DNA methylation in female adult progeny.Communications biology · 2025Article
- Associations of aeroallergen testing with reduced oral corticosteroid bursts among adults with asthma.The journal of allergy and clinical immunology. Global · 2025Article
- Cell-Specific Contribution of IL-4 Receptor α Signaling Shapes the Overall Manifestation of Allergic Airway Disease.American journal of respiratory cell and molecular biology · 2024Article
- Minimizing Indoor Allergen Exposure: What Works?Current allergy and asthma reports · 2024Review
- Questionnaire Development to Assess Risk Factors for Environmental Diseases of Children in Daejeon.Journal of clinical medicine · 2024Article
- Article
- Multilevel Risk Factors for Sleep-Disordered Breathing-Related Symptom Burden in an Urban Pediatric Community-Based Sample.CHEST pulmonary · 2023Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe National Survey of Lead and Allergens in Housing was the first population-based study to measure indoor allergen levels in US homes.
objectiveWe characterized the overall burden to multiple allergens and examined whether increased allergen levels were associated with occupants' asthma status.
methodsThis cross-sectional study surveyed a nationally representative sample of 831 housing units in 75 different locations throughout the United States. Information was collected by means of questionnaire and environmental assessment. Allergen concentrations in dust samples were assessed by using immunoassays. The following cutoff points were used to define increased allergen levels: 10 microg/g for Der p 1, Der f 1, and Can f 1; 8 microg/g for Fel d 1; 8 U/g for Bla g 1; 1.6 microg/g for mouse urinary protein; and 7 microg/g for Alternaria alternata antigens. Allergen burden was considered high when 4 or more allergens exceeded increased levels in any of the sampling locations.
resultsExposure to multiple allergens was common in US homes. Of the surveyed homes, 51.5% had at least 6 detectable allergens and 45.8% had at least 3 allergens exceeding increased levels. Race, income, housing type, absence of children, and presence of smokers, pets, cockroaches, rodents, and mold/moisture-related problems were independent predictors of high allergen burden. Among atopic subjects, high allergen burden increased the odds of having asthma symptoms (odds ratio, 1.81; 95% CI, 1.04-3.15).
conclusionIncreased allergen levels in the home are associated with asthma symptoms in allergic individuals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.