Evidence map›Paper›PMID 18254964›Full record

ArticleBMC public health2008

A longitudinal study of environmental tobacco smoke exposure in children: parental self reports versus age dependent biomarkers.

Carme Puig, Oscar Garcia-Algar, Toni Monleon, Roberta Pacifici, Piergiorgio Zuccaro, Jordi Sunyer, Cecilia Figueroa, Simona Pichini, Oriol Vall

Abstract read
In one paragraph

Article in BMC public health, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Transgenerational exposure to environmental tobacco smoke.International journal of environmental research and public health · 2014
    Review
  9. Observational
  10. Article
  11. Article
  12. Umbilical cord blood cotinine and smoking during pregnancy.Journal of perinatology : official journal of the California Perinatal Association · 2012
    Article
  13. Recent contributions of air- and biomarkers to the control of secondhand smoke (SHS): a review.International journal of environmental research and public health · 2011
    Review
  14. Concentration of metals in blood of Maine children 1-6 years old.Journal of exposure science & environmental epidemiology · 2010
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carme PuigEnvironmental and Pediatric Research Unit (URIE), Pediatric Department, Hospital del Mar, Barcelona, Spain. carmepuig@yahoo.es
Oscar Garcia-Algar
Toni Monleon
Roberta Pacifici
Piergiorgio Zuccaro
Jordi Sunyer
Cecilia Figueroa
Simona Pichini
Oriol Vall

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAwareness of the negative effects of smoking on children's health prompted a decrease in the self-reporting of parental tobacco use in periodic surveys from most industrialized countries. Our aim is to assess changes between ETS exposure at the end of pregnancy and at 4 years of age determined by the parents' self-report and measurement of cotinine in age related biological matrices.

methodsThe prospective birth cohort included 487 infants from Barcelona city (Spain). Mothers were asked about maternal and household smoking habit. Cord serum and children's urinary cotinine were analyzed in duplicate using a double antibody radioimmunoassay.

resultsAt 4 years of age, the median urinary cotinine level in children increased 1.4 or 3.5 times when father or mother smoked, respectively. Cotinine levels in children's urine statistically differentiated children from smoking mothers (Geometric Mean (GM) 19.7 ng/ml; 95% CI 16.83-23.01) and exposed homes (GM 7.1 ng/ml; 95% CI 5.61-8.99) compared with non-exposed homes (GM 4.5 ng/ml; 95% CI 3.71-5.48). Maternal self-reported ETS exposure in homes declined in the four year span between the two time periods from 42.2% to 31.0% (p < 0.01). Nevertheless, most of the children considered non-exposed by their mothers had detectable levels of cotinine above 1 ng/mL in their urine.

conclusionWe concluded that cotinine levels determined in cord blood and urine, respectively, were useful for categorizing the children exposed to smoking and showed that a certain increase in ETS exposure during the 4-year follow-up period occurred.

Indexed as

MothersAnalysis of VarianceBiomarkersChild, PreschoolCohort StudiesCotinineEnvironmental ExposureFemaleFetal BloodHumansInfant, NewbornMaleTobacco Smoke PollutionBiomarkersCotinineTobacco Smoke Pollution

Identifiers

PMID18254964
PMCPMC2276212

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.