ArticlePloS one2008
Comparative bacterial proteomics: analysis of the core genome concept.
Article in PloS one, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- A local-scale One Health genomic surveillance ofMicrobial genomics · 2023Article
- "Omics" Technologies - What Have They Told Us About UropathogenicFrontiers in cellular and infection microbiology · 2022Review
- Genome Mining of the GenusGenes · 2020Article
- Genetic Variants of the DSF Quorum Sensing System inFrontiers in microbiology · 2020Article
- 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.Nature biotechnology · 2019Article
- A degeneration-reducing criterion for optimal digital mapping of genetic codes.Computational and structural biotechnology journal · 2019Article
- Metaproteomics analysis of microbial diversity of human saliva and tongue dorsum in young healthy individuals.Journal of oral microbiology · 2019Article
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- Major Traditional Probiotics: Comparative Genomic Analyses and Roles in Gut Microbiome of Eight Cohorts.Frontiers in microbiology · 2019Article
- BPSL1626: Reverse and Structural Vaccinology Reveal a Novel Candidate for Vaccine Design againstAntibodies (Basel, Switzerland) · 2018Article
- Article
- Comparative Analysis of Secretome Profiles of Manganese(II)-Oxidizing Ascomycete Fungi.PloS one · 2016Article
- Comparative Proteomic Analysis of Desulfotomaculum reducens MI-1: Insights into the Metabolic Versatility of a Gram-Positive Sulfate- and Metal-Reducing Bacterium.Frontiers in microbiology · 2016Article
- The Pacific Northwest National Laboratory library of bacterial and archaeal proteomic biodiversity.Scientific data · 2015Article
- Construction of a dairy microbial genome catalog opens new perspectives for the metagenomic analysis of dairy fermented products.BMC genomics · 2014Article
- Genomic encyclopedia of type strains of the genus Bifidobacterium.Applied and environmental microbiology · 2014Article
- Systems biology perspectives on minimal and simpler cells.Microbiology and molecular biology reviews : MMBR · 2014Review
- SPOCS: software for predicting and visualizing orthology/paralogy relationships among genomes.Bioinformatics (Oxford, England) · 2013Article
- Expression divergence between Escherichia coli and Salmonella enterica serovar Typhimurium reflects their lifestyles.Molecular biology and evolution · 2013Article
- By their genes ye shall know them: genomic signatures of predatory bacteria.The ISME journal · 2013Article
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8 authors.
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Abstract
While comparative bacterial genomic studies commonly predict a set of genes indicative of common ancestry, experimental validation of the existence of this core genome requires extensive measurement and is typically not undertaken. Enabled by an extensive proteome database developed over six years, we have experimentally verified the expression of proteins predicted from genomic ortholog comparisons among 17 environmental and pathogenic bacteria. More exclusive relationships were observed among the expressed protein content of phenotypically related bacteria, which is indicative of the specific lifestyles associated with these organisms. Although genomic studies can establish relative orthologous relationships among a set of bacteria and propose a set of ancestral genes, our proteomics study establishes expressed lifestyle differences among conserved genes and proposes a set of expressed ancestral traits.
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