ReviewCell metabolism2008
Fighting fat with muscle: bulking up to slim down.
Review in Cell metabolism, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- 5,7-Dimethoxyflavone Attenuates Obesity-Associated Muscle Atrophy via AMPK and PI3K/Akt Pathways inJournal of microbiology and biotechnology · 2026Article
- Exploring the Effective Components and Mechanism of Action of JapanesePharmaceuticals (Basel, Switzerland) · 2022Article
- StandardizedEvidence-based complementary and alternative medicine : eCAM · 2018Article
- Impact of placental insufficiency on fetal skeletal muscle growth.Molecular and cellular endocrinology · 2016Review
- Gut microbiota can transfer fiber characteristics and lipid metabolic profiles of skeletal muscle from pigs to germ-free mice.Scientific reports · 2016Article
- A role for circadian clock in metabolic disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Review
- Measurement of body composition as a surrogate evaluation of energy balance in obese patients.World journal of methodology · 2015Review
- Muscular fitness and clustered cardiovascular disease risk in Australian youth.European journal of applied physiology · 2012Article
- An atlas of DNA methylomes in porcine adipose and muscle tissues.Nature communications · 2012Article
- Whole transcriptome analysis of the fasting and fed Burmese python heart: insights into extreme physiological cardiac adaptation.Physiological genomics · 2011Article
- Article
- Glucocorticoid regulation of the circadian clock modulates glucose homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Akt1 is a well-characterized mediator of muscle hypertrophy. In this issue of Cell Metabolism, Izumiya et al. (2008) reveal a striking link between Akt1 signaling, fast muscle fiber size, and whole-body metabolism. These results provide new insights into the ability of muscle to combat diet-induced obesity and metabolic dysfunction.
Indexed as
Identifiers
18249167What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.