ArticleObesity surgery2008
Gastric bypass surgery causes body weight loss without reducing food intake in rats.
Article in Obesity surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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Who cites it
19 citing papers in PubMed.
- Effects of gastric bypass on the digestibility and postprandial metabolic fate of 15N dietary protein in rats.PloS one · 2024Article
- Meal Patterns and Food Choices of Female Rats Fed a Cafeteria-Style Diet Are Altered by Gastric Bypass Surgery.Nutrients · 2021Article
- Meal patterns after bariatric surgery in mice and rats.Appetite · 2020Review
- Hyperoxaluria in a Model of Mini-Gastric Bypass Surgery in Rats.Obesity surgery · 2017Article
- Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action.Obesity surgery · 2017Article
- Roux-en-Y gastric bypass: effects on feeding behavior and underlying mechanisms.The Journal of clinical investigation · 2015Review
- Appetite and body weight regulation after bariatric surgery.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2015Review
- Steatorrhea and hyperoxaluria occur after gastric bypass surgery in obese rats regardless of dietary fat or oxalate.The Journal of urology · 2013Article
- Longitudinal assessment of food intake, fecal energy loss, and energy expenditure after Roux-en-Y gastric bypass surgery in high-fat-fed obese rats.Obesity surgery · 2013Article
- Mechanistic comparison between gastric bypass vs. duodenal switch with sleeve gastrectomy in rat models.PloS one · 2013Article
- Eating behavior and glucagon-like peptide-1-producing cells in interposed ileum and pancreatic islets in rats subjected to ileal interposition associated with sleeve gastrectomy.Obesity surgery · 2013Article
- Experimental metabolic surgery: justification and technical aspects.Obesity surgery · 2011Article
- Gastrectomy alters emotional reactivity in rats: neurobiological mechanisms.The European journal of neuroscience · 2011Article
- Lessons learned from gastric bypass operations in rats.Obesity facts · 2011Review
- Eating behavior in rats subjected to vagotomy, sleeve gastrectomy, and duodenal switch.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2010Article
- Vagal sparing surgical technique but not stoma size affects body weight loss in rodent model of gastric bypass.Obesity surgery · 2010Article
- Roux-en-Y gastric bypass enhances energy expenditure and extends lifespan in diet-induced obese rats.Obesity (Silver Spring, Md.) · 2009Article
- Development of obesity is associated with increased calories per meal rather than per day. A study of high-fat diet-induced obesity in young rats.Obesity surgery · 2009Article
- A higher meal frequency may be associated with diminished weight loss after bariatric surgery.Clinics (Sao Paulo, Brazil) · 2009Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is a common dogma that gastric bypass (GB) induces early satiety and consequent reductions in food intake and nutrient absorption. The aim of the present study was to analyze feeding behavioral and metabolic changes in rats after GB.
methodsMale Sprague-Dawley rats at the ages of 23 and 42 weeks were placed in metabolic cages connected with a comprehensive laboratory animal monitoring system. At the age of 48 weeks they were subjected to either GB or sham operation, and then placed in metabolic cages at 51 and 62 weeks (or 3 and 14 weeks postoperatively).
resultsGB rats lost 20% of the body weight within 2-3 weeks and remained at this lower level until the end of the study at 14 weeks postoperatively. Satiety ratio was higher during daytime than nighttime in both sham-operated and GB rats, but was not significantly different between the two groups. Neither daily accumulated food intake nor food intake per 100 g of body weight was different between sham-operated and GB rats. Apparently, GB rats ate more frequently during daytime and had smaller meal size during nighttime at 3 weeks postoperatively. These changes were not present at 14 weeks postoperatively. Energy density in the feces was the same in GB and sham-operated rats postoperatively. Energy expenditure declined with age, but increased in GB rats compared with age-matched sham-operated rats.
conclusionsGB reduced the body weight without causing early satiety, reducing food intake or inducing malabsorption. It did, however, increase energy expenditure.
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Registered trials
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