ReviewEMBO reports2008
Once in a lifetime: strategies for preventing re-replication in prokaryotic and eukaryotic cells.
Review in EMBO reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Changing Perspectives on the Role of DnaA-ATP in Orisome Function and Timing Regulation.Frontiers in microbiology · 2019Review
- Fundamental principles in bacterial physiology-history, recent progress, and the future with focus on cell size control: a review.Reports on progress in physics. Physical Society (Great Britain) · 2018Review
- Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective.Frontiers in microbiology · 2018Review
- Inevitability and containment of replication errors for eukaryotic genome lengths spanning megabase to gigabase.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- DNA Methylation.EcoSal Plus · 2014Article
- Initiator protein dimerization plays a key role in replication control of Vibrio cholerae chromosome 2.Nucleic acids research · 2014Article
- Article
- Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.BMC genomics · 2012Article
- Helicobacter pylori oriC--the first bipartite origin of chromosome replication in Gram-negative bacteria.Nucleic acids research · 2012Article
- Replication regulation of Vibrio cholerae chromosome II involves initiator binding to the origin both as monomer and as dimer.Nucleic acids research · 2012Article
- Genome-wide detection of chromosomal rearrangements, indels, and mutations in circular chromosomes by short read sequencing.Genome research · 2011Article
- Transition from a plasmid to a chromosomal mode of replication entails additional regulators.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Initiation of DNA Replication.EcoSal Plus · 2010Article
- Replication of Vibrio cholerae chromosome I in Escherichia coli: dependence on dam methylation.Journal of bacteriology · 2010Article
- DNA adenine methylation is required to replicate both Vibrio cholerae chromosomes once per cell cycle.PLoS genetics · 2010Article
- Primase directs the release of DnaC from DnaB.Molecular cell · 2010Article
- Protein and DNA effectors control the TraI conjugative helicase of plasmid R1.Journal of bacteriology · 2009Article
- The right half of the Escherichia coli replication origin is not essential for viability, but facilitates multi-forked replication.Molecular microbiology · 2009Article
- Replication initiator DnaA of Escherichia coli changes its assembly form on the replication origin during the cell cycle.Journal of bacteriology · 2009Article
- DnaAcos hyperinitiates by circumventing regulatory pathways that control the frequency of initiation in Escherichia coli.Molecular microbiology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA replication is an extremely accurate process and cells have evolved intricate control mechanisms to ensure that each region of their genome is replicated only once during S phase. Here, we compare what is known about the processes that prevent re-replication in prokaryotic and eukaryotic cells by using the model organisms Escherichia coli and Schizosaccharomyces pombe as examples. Although the underlying molecular details are different, the logic behind the control mechanisms is similar. For example, after initiation, crucial molecules required for the loading of replicative helicases in both prokaryotes and eukaryotes are inactivated until the next cell cycle. Furthermore, in both systems the beta-clamp of the replicative polymerase associates with enzymatic activities that contribute to the inactivation of the helicase loaders. Finally, recent studies suggest that the control mechanism that prevents re-replication in both systems also increases the synthesis of DNA building blocks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.