ArticleGenetics2008
Evidence of spatially varying selection acting on four chromatin-remodeling loci in Drosophila melanogaster.
Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Influence of geography, seasonality and experimental selection on Chironomus riparius recombination rates.BMC genomics · 2026Article
- Chameau (HBO1) regulates starvation resistance inLife science alliance · 2026Article
- Gene and transposable element expression in response to stress in temperate and tropical populations of Drosophila.Mobile DNA · 2025Article
- Polycomb group proteins confer robustness to aposematic coloration in the milkweed bug,Proceedings. Biological sciences · 2024Article
- Genetic diversity of a Silybum marianum (L.) Gaertn. germplasm collection revealed by DNA Diversity Array Technology (DArTseq).PloS one · 2024Article
- The fruit fly acetyltransferase chameau promotes starvation resilience at the expense of longevity.EMBO reports · 2023Article
- Histone methylation regulates reproductive diapause in Drosophila melanogaster.PLoS genetics · 2023Article
- The Paramount Role ofInsects · 2021Review
- Differences in temperature-sensitive expression of PcG-regulated genes among natural populations of Drosophila melanogaster.G3 (Bethesda, Md.) · 2021Article
- Decreased Temperature Sensitivity ofGenes · 2019Article
- Article
- A Hidden Markov Model Approach for Simultaneously Estimating Local Ancestry and Admixture Time Using Next Generation Sequence Data in Samples of Arbitrary Ploidy.PLoS genetics · 2017Article
- Molecular Evolution of Drosophila Germline Stem Cell and Neural Stem Cell Regulating Genes.Genome biology and evolution · 2015Article
- Evolutionary genomics of Culex pipiens: global and local adaptations associated with climate, life-history traits and anthropogenic factors.Proceedings. Biological sciences · 2015Article
- Article
- Article
- Segregating variation in the polycomb group gene cramped alters the effect of temperature on multiple traits.PLoS genetics · 2011Article
- Genomic differentiation between temperate and tropical Australian populations of Drosophila melanogaster.Genetics · 2011Article
- Whole-genome expression plasticity across tropical and temperate Drosophila melanogaster populations from Eastern Australia.Molecular biology and evolution · 2011Article
- Article
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Authors and funding
2 authors.
Funding
Abstract
The packaging of DNA into proper chromatin structure contributes to transcriptional regulation. This packaging is environment sensitive, yet its role in adaptation to novel environmental conditions is completely unknown. We set out to identify candidate chromatin-remodeling loci that are differentiated between tropical and temperate populations in Drosophila melanogaster, an ancestrally equatorial African species that has recently colonized temperate environments around the world. Here we describe sequence variation at seven such chromatin-remodeling loci, four of which (chd1, ssrp, chm, and glu) exhibit strong differentiation between tropical and temperate populations. An in-depth analysis of chm revealed sequence differentiation restricted to a small portion of the gene, as well as evidence of clinal variation along the east coasts of both the United States and Australia. The functions of chd1, chm, ssrp, and glu point to several novel hypotheses for the role of chromatin-based transcriptional regulation in adaptation to a novel environment. Specifically, both stress-induced transcription and developmental homeostasis emerge as potential functional targets of environment-dependent selection.
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