Evidence map›Paper›PMID 18245564›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2008

Effects of posture on shear rates in human brachial and superficial femoral arteries.

S C Newcomer, C L Sauder, N T Kuipers, M H Laughlin, C A Ray

Abstract readComparative Study
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Trial
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  5. Pre- and Post-Interventional Hemodynamic Characterization of the Femoropopliteal Artery Using Vector Flow Imaging in Peripheral Arterial Occlusive Disease.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  6. Article
  7. Supine hypertension: hemodynamic and neurohumoral mechanisms-reflections on the hypertension research update and perspectives 2025.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  8. Article
  9. Article
  10. Article
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  13. Article
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  16. Article
  17. Article
  18. A tale of three cuffs: the hemodynamics of blood flow restriction.European journal of applied physiology · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

S C NewcomerPurdue University, Dept. of Health and Kinesiology, West Lafayette, IN 47907, USA. snewcome@purdue.edu
C L Sauder
N T Kuipers
M H Laughlin
C A Ray

Funding

WRITING AND THE DAILY EXPERIENCE OF ILLNESSM01RR010732 · NCRR · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MACNEILL, COLIN · 1995 to 2009
$29.8M
Vascular Biology: Exercise Training and Vascular DiseaseP01HL052490 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI PRICE, ELMER M · 1995 to 2010
$19.3M
Sympathetic/Cardiopulmonary Regulation by Vestibular RefP01HL077670 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LEUENBERGER, URS A · 2004 to 2008
$6.9M
TRAINING: MUSCLE BLOOD FLOW &CAPILLARY DYNAMICSR01HL036088 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI LAUGHLIN, M HAROLD · 1985 to 2013
$4.0M
Vestibulosympathetic Reflexes in HumansR01DC006459 · NIDCD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI RAY, CHESTER A · 2003 to 2005
$817k
Influence of blood pressure on PAD distributionF32HL083597 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI NEWCOMER, SEAN C · 2006 to 2007
$63k
NCRR NIH HHS M01 RR010732NCRR NIH HHS M01-RR-10732NHLBI NIH HHS F32 HL083597NHLBI NIH HHS HL-07760NHLBI NIH HHS HL-083597NHLBI NIH HHS HL-36088NHLBI NIH HHS HL-52490NHLBI NIH HHS P01 HL052490NHLBI NIH HHS P01 HL077670NHLBI NIH HHS R01 HL036088NIDCD NIH HHS DC-006459NIDCD NIH HHS R01 DC006459
6 · The paper itself

Abstract

Shear rate is significantly lower in the superficial femoral compared with the brachial artery in the supine posture. The relative shear rates in these arteries of subjects in the upright posture (seated and/or standing) are unknown. The purpose of this investigation was to test the hypothesis that upright posture (seated and/or standing) would produce greater shear rates in the superficial femoral compared with the brachial artery. To test this hypothesis, Doppler ultrasound was used to measure mean blood velocity (MBV) and diameter in the brachial and superficial femoral arteries of 21 healthy subjects after being in the supine, seated, and standing postures for 10 min. MBV was significantly higher in the brachial compared with the superficial femoral artery during upright postures. Superficial femoral artery diameter was significantly larger than brachial artery diameter. However, posture had no significant effect on either brachial or superficial femoral artery diameter. The calculated shear rate was significantly greater in the brachial (73 +/- 5, 91 +/- 11, and 97 +/- 13 s(-1)) compared with the superficial femoral (53 +/- 4, 39 +/- 77, and 44 +/- 5 s(-1)) artery in the supine, seated, and standing postures, respectively. Contrary to our hypothesis, our current findings indicate that mean shear rate is lower in the superficial femoral compared with the brachial artery in the supine, seated, and standing postures. These findings of lower shear rates in the superficial femoral artery may be one mechanism for the higher propensity for atherosclerosis in the arteries of the leg than of the arm.

Indexed as

PostureAdultBlood Flow VelocityBlood PressureBrachial ArteryFemaleFemoral ArteryHeart RateHemorheologyHumansLaser-Doppler FlowmetryMaleReference ValuesRegional Blood FlowUltrasonography

Identifiers

PMID18245564
PMCPMC3289057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.