Evidence map›Paper›PMID 18245275›Full record

ArticleEukaryotic cell2008

A ferroxidase encoded by FOX1 contributes to iron assimilation under conditions of poor iron nutrition in Chlamydomonas.

Jen-Chih Chen, Scott I Hsieh, Janette Kropat, Sabeeha S Merchant

Open access · diamondAbstract read
In one paragraph

Article in Eukaryotic cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. From economy to luxury: Copper homeostasis in Chlamydomonas and other algae.Biochimica et biophysica acta. Molecular cell research · 2020
    Review
  6. Regulation of Iron Homeostasis and Use in Chloroplasts.International journal of molecular sciences · 2020
    Review
  7. Article
  8. Regulating cellular trace metal economy in algae.Current opinion in plant biology · 2017
    Review
  9. Article
  10. Article
  11. Remodeling of membrane lipids in iron-starved Chlamydomonas.The Journal of biological chemistry · 2013
    Article
  12. Article
  13. Article
  14. The ins and outs of algal metal transport.Biochimica et biophysica acta · 2012
    Review
  15. Article
  16. Review
  17. Disassembling iron availability to phytoplankton.Frontiers in microbiology · 2012
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jen-Chih ChenDepartment of Chemistry and Biochemistry, Box 951569, University of California-Los Angeles, Los Angeles, CA 90095-1569, USA.
Scott I Hsieh
Janette Kropat
Sabeeha S Merchant
University of California, Los Angeles · US

Funding

UCLA NIGMS T32 Program AssessmentT32GM007185 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TORRES, JORGE · 1985 to 2020
$21.7M
Nutritional Cu Signaling and HomeostasisR01GM042143 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SABEEHA MERCHANT · 1995 to 2026
$4.6M
Nutritional Copper Signaling and HomeostasisR37GM042143 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MERCHANT, SABEEHA · 2011 to 2020
$4.3M
CU-DEPENDENT TRANSCRIPTIONAL REGULATIONR29GM042143 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MERCHANT, SABEEHA · 1989 to 1993
–
NIGMS NIH HHS GM07185NIGMS NIH HHS GM42143NIGMS NIH HHS R01 GM042143NIGMS NIH HHS R37 GM042143NIGMS NIH HHS T32 GM007185
6 · The paper itself

Abstract

When the abundance of the FOX1 gene product is reduced, Chlamydomonas cells grow poorly in iron-deficient medium, but not in iron-replete medium, suggesting that FOX1-dependent iron uptake is a high-affinity pathway. Alternative pathways for iron assimilation, such as those involving ZIP family transporters IRT1 and IRT2, may be operational.

Indexed as

AnimalsCation Transport ProteinsCeruloplasminChlamydomonas reinhardtiiIronMembrane Transport ProteinsCation Transport ProteinsCeruloplasminIronMembrane Transport Proteins

Identifiers

PMID18245275
PMCPMC2268516
OpenAlexW2152729331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.