Evidence map›Paper›PMID 18243095›Full record

ReviewCell2008

Evo-devo: variations on ancestral themes.

E M De Robertis

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers.

0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

135 citing papers in PubMed, 337 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Reflections on Model Species in Evolutionary Developmental Biology.Results and problems in cell differentiation · 2026
    Review
  6. Building the parasitic waspFrontiers in insect science · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Molecular analysis of a self-organizing signaling pathway forProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Evolutionary immunology to explore original antiviral strategies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Context-dependent TGFβ family signalling in cell fate regulation.Nature reviews. Molecular cell biology · 2023
    Review
  16. Review
  17. Article
  18. A pro-BMP function exerted byOpen biology · 2023
    Article
  19. Review
  20. Bmp4 Synexpression Gene,International journal of molecular sciences · 2022
    Article

75 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

E M De RobertisHoward Hughes Medical Institute and Department of Biological Chemistry, University of California, Los Angeles, CA 90095-1662, USA. ederobertis@mednet.ucla.edu
University of California, Los Angeles · US

Funding

HOMEOBOX GENES AND THEIR TARGETS IN XENOPUS DEVELOPMENTR37HD021502 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DE ROBERTIS, EDWARD M · 1997 to 2006
$2.2M
HOMEOBOXES IN XENOPUS DEVELOPMENTR01HD021502 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DE ROBERTIS, EDWARD M · 1986 to 2011
$1.6M
NICHD NIH HHS HD21502-21NICHD NIH HHS R01 HD021502NICHD NIH HHS R37 HD021502
6 · The paper itself

Abstract

Most animals evolved from a common ancestor, Urbilateria, which already had in place the developmental genetic networks for shaping body plans. Comparative genomics has revealed rather unexpectedly that many of the genes present in bilaterian animal ancestors were lost by individual phyla during evolution. Reconstruction of the archetypal developmental genomic tool-kit present in Urbilateria will help to elucidate the contribution of gene loss and developmental constraints to the evolution of animal body plans.

Indexed as

Biological EvolutionGenetic VariationAnimalsBody PatterningDevelopmental BiologyGene DeletionGene DuplicationGenes, HomeoboxGenomeMicroRNAsModels, BiologicalMutationPhylogenyRegulatory Elements, TranscriptionalSignal TransductionMicroRNAs

Identifiers

PMID18243095
PMCPMC2280037
OpenAlexW2152839099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.