Trial reportJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: rationale and design of a prospective, multicenter trial.
Trial report in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Myocardial perfusion imaging and risk classification for coronary heart disease in diabetic patients. The IDIS study: a prospective, multicentre trial.European journal of nuclear medicine and molecular imaging · 2012Trial
- Relationship between vascular stiffness and stress myocardial perfusion imaging in asymptomatic patients with diabetes.European journal of nuclear medicine and molecular imaging · 2011Trial
- Long-term prognostic value of coronary artery calcium scanning, coronary computed tomographic angiography and stress myocardial perfusion imaging in patients with suspected coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Coronary atherosclerotic burden vs. coronary vascular function in diabetic and nondiabetic patients with normal myocardial perfusion: a propensity score analysis.European journal of nuclear medicine and molecular imaging · 2017Article
- Quantitative relationship between coronary artery calcium and myocardial blood flow by hybrid rubidium-82 PET/CT imaging in patients with suspected coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Cardiovascular risk stratification in diabetic patients: is all in METS?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Article
- Survival analysis and regression models.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Review
- Detection of silent myocardial ischemia: is it clinically relevant?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- Microalbuminuria predicts silent myocardial ischaemia in type 2 diabetes patients.European journal of nuclear medicine and molecular imaging · 2013Article
- Transient ischemic dilation in SPECT myocardial perfusion imaging for prediction of severe coronary artery disease in diabetic patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013Article
- Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease.European journal of nuclear medicine and molecular imaging · 2012Article
- Myocardial perfusion imaging: a plus for coronary risk classification in diabetics.European journal of nuclear medicine and molecular imaging · 2012Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA prospective, multicenter trial has been designed to evaluate the impact of inducible ischemia by stress single photon emission computed tomography (SPECT) in diabetic patients and to define the role of SPECT in assessing the cardiac risk in such patients. This report presents the details and implications of the Impact of Inducible Ischemia by Stress SPECT (IDIS) trial design. METHODS AND
resultsBetween January 2002 and September 2005, 1006 consecutive patients (649 men and 357 women; mean age, 63 +/- 9 years) with at least a 5-year history of type 2 diabetes mellitus were enrolled. All patients underwent stress-rest sestamibi SPECT imaging with physical exercise (n = 573) or dipyridamole (n = 433). SPECT studies will be analyzed by use of a 17-segment scoring system to calculate left ventricular ejection fraction, summed stress score, summed rest score, and summed difference score. The SPECT study will be considered abnormal if the summed stress score is 3 or greater. Patients with abnormal studies will be considered to have ischemia if the summed difference score is 2 or greater.
conclusionThe results of this trial should help to define the role of SPECT in assessing cardiac risk in diabetic patients. Furthermore, this trial will prospectively evaluate subsequent patient outcome during long-term follow-up.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.