Trial reportPediatric blood & cancer2008
Influenza-associated morbidity in children with cancer.
Trial report in Pediatric blood & cancer, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 66 citations in OpenAlex.
- Trial
- Safety of high dose trivalent inactivated influenza vaccine in pediatric patients with acute lymphoblastic leukemia.Pediatric blood & cancer · 2014Trial
- Trial
- Implementation factors and healthcare provider willingness to vaccinate in Latin America and the Caribbean.Journal of health, population, and nutrition · 2025Article
- Immunization coverage for children with cancer in Latin America and the Caribbean can be improved through strategic coordination of existing global agendas.Human vaccines & immunotherapeutics · 2025Article
- Boosting the influenza vaccine schedule in children with cancer: a prospective open-label study.NPJ vaccines · 2025Article
- COVID-19 burden of illness in people who are immunocompromised due to cancer: an expert opinion review.The oncologist · 2025Review
- Seasonal Influenza in Children With Cancer.Cureus · 2024Review
- Contribution of immunoglobulin products in influencing seasonal influenza infection and severity in antibody immune deficiency patients receiving immunoglobulin replacement therapy.Frontiers in immunology · 2024Review
- Generation of Human Lung Organoid Cultures from Healthy and Tumor Tissue to Study Infectious Diseases.Journal of virology · 2022Article
- Epidemiology and clinical characteristics of viral infections in hospitalized children and adolescents with cancer in Lebanon.PloS one · 2020Article
- Vaccination against influenza at a European pediatric cancer center: immunization rates and attitudes among staff, patients, and their families.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
- Immunogenicity and clinical effectiveness of the trivalent inactivated influenza vaccine in immunocompromised children undergoing treatment for cancer.Cancer medicine · 2016Article
- Burden of Influenza-Related Hospitalizations and Attributable Mortality in Pediatric Acute Lymphoblastic Leukemia.Journal of the Pediatric Infectious Diseases Society · 2015Article
- Human rhinovirus C infections in pediatric hematology and oncology patients.Pediatric transplantation · 2015Article
- Guidelines on vaccinations in paediatric haematology and oncology patients.BioMed research international · 2014Review
- A prospective study of chemotherapy immunologic effects and predictors of humoral influenza vaccine responses in a pediatric oncology cohort.Influenza and other respiratory viruses · 2013Article
- Protecting pediatric oncology patients from influenza.The oncologist · 2013Review
- Clinical and demographic characteristics of seasonal influenza in pediatric patients with cancer.The Pediatric infectious disease journal · 2012Article
- Novel influenza A (H1N1) 2009 infection in the pediatric patients with hematologic and oncologic diseases in the Yeungnam region.Korean journal of pediatrics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe clinical impact of influenza in children undergoing therapy for cancer is not well-described in the literature. PROCEDURE: Laboratory-documented influenza infection in pediatric oncology patients cared for in a single regional pediatric medical center between July 2000 and June 2005 was identified by review of medical and laboratory records.
resultsTwenty-seven clinical encounters were identified in 24 pediatric oncology patients with influenza infection. Eighty-three percent of patients were receiving chemotherapy for hematologic or solid malignancies. Two-thirds of patients were hospitalized for a median duration of 7.4 days; 40% of patients experienced a delay in scheduled chemotherapy as result of influenza infection. Most children (67%) were not neutropenic, although 63% were lymphopenic. Importantly, 15% of children with influenza had simultaneously diagnosed bacteremia. Concomitant pathogens included Pseudomonas aeruginosa, Enterobacter cloacae, Enterococcus faecalis, and coagulase-negative Staphylococcus. Primary influenza pneumonia and/or respiratory failure occurred in three children, and ventilatory support was required in four clinical encounters. Antiviral medications were administered to 63% of patients within 2 days of influenza diagnosis.
conclusionPediatric oncology patients experienced significant influenza-associated morbidities. Influenza infection should be considered in febrile children with respiratory symptoms during the respiratory viral season, as well as concurrent bacterial or fungal infections.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.