ArticleThe Plant cell2008
Epigenetic modification of centromeric chromatin: hypomethylation of DNA sequences in the CENH3-associated chromatin in Arabidopsis thaliana and maize.
Article in The Plant cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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Who cites it
81 citing papers in PubMed, 170 citations in OpenAlex.
- Augmented CENH3 loading is accompanied by transcriptional and epigenetic reprogramming at rice centromeres during meiosis.Genome biology · 2026Article
- Largest genome assembly in Brassicaceae: retrotransposon-driven genome expansion and karyotype evolution in Matthiola incana.Plant biotechnology journal · 2025Article
- Generation and characterization of rice OsCENH3 mutants for haploid induction.Plant cell reports · 2025Article
- Four near-complete genome assemblies reveal the landscape and evolution of centromeres in Salicaceae.Genome biology · 2025Article
- Conservation of dichromatin organization along regional centromeres.Cell genomics · 2025Article
- Retrotransposon addiction promotes centromere function via epigenetically activated small RNAs.Nature plants · 2024Article
- The Chaperone NASP Contributes to de Novo Deposition of the Centromeric Histone Variant CENH3 in Arabidopsis Early Embryogenesis.Plant & cell physiology · 2024Article
- Near telomere-to-telomere genome assemblies of two Chlorella species unveil the composition and evolution of centromeres in green algae.BMC genomics · 2024Article
- The MRE11-ATM-SOG1 DNA damage signaling pathway confers rice immunity to Xanthomonas oryzae.Plant communications · 2024Article
- High-quality Gossypium hirsutum and Gossypium barbadense genome assemblies reveal the landscape and evolution of centromeres.Plant communications · 2024Article
- A near-complete genome assembly of the allotetrapolyploid Cenchrus fungigraminus (JUJUNCAO) provides insights into its evolution and C4 photosynthesis.Plant communications · 2023Article
- Centromere repositioning and shifts in wheat evolution.Plant communications · 2023Article
- Oligo-FISH ofInternational journal of molecular sciences · 2023Article
- Cold-induced inhibition of photosynthesis-related genes integrated by a TOP6 complex in rice mesophyll cells.Nucleic acids research · 2023Article
- Epigenetic nature of Arabidopsis thaliana telomeres.Plant physiology · 2023Article
- Extended DNA Fibers for High-Resolution Mapping.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Genome-Wide Identification of NAP1 and Function Analysis in Moso Bamboo (International journal of molecular sciences · 2022Article
- An improved Raphanus sativus cv. WK10039 genome localizes centromeres, uncovers variation of DNA methylation and resolves arrangement of the ancestral Brassica genome blocks in radish chromosomes.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- The genetics and epigenetics of satellite centromeres.Genome research · 2022Article
- High-quality Arabidopsis thaliana Genome Assembly with Nanopore and HiFi Long Reads.Genomics, proteomics & bioinformatics · 2022Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The centromere in eukaryotes is defined by the presence of a special histone H3 variant, CENH3. Centromeric chromatin consists of blocks of CENH3-containing nucleosomes interspersed with blocks of canonical H3-containing nucleosomes. However, it is not known how CENH3 is precisely deposited in the centromeres. It has been suggested that epigenetic modifications of the centromeric chromatin may play a role in centromere identity. The centromeres of Arabidopsis thaliana are composed of megabase-sized arrays of a 178-bp satellite repeat. Here, we report that the 178-bp repeats associated with the CENH3-containing chromatin (CEN chromatin) are hypomethylated compared with the same repeats located in the flanking pericentromeric regions. A similar hypomethylation of DNA in CEN chromatin was also revealed in maize (Zea mays). Hypomethylation of the DNA in CEN chromatin is correlated with a significantly reduced level of H3K9me2 in Arabidopsis. We demonstrate that the 178-bp repeats from CEN chromatin display a distinct distribution pattern of the CG and CNG sites, which may provide a foundation for the differential methylation of these repeats. Our results suggest that DNA methylation plays an important role in epigenetic demarcation of the CEN chromatin.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.