Evidence map›Paper›PMID 18236451›Full record

ArticleThe International journal of eating disorders2008

The genetics of anorexia nervosa collaborative study: methods and sample description.

Walter H Kaye, Cynthia M Bulik, Katherine Plotnicov, Laura Thornton, Bernie Devlin, Manfred M Fichter, Janet Treasure, Allan Kaplan, D Blake Woodside, Craig L Johnson and 7 more

Abstract readMulticenter Study
In one paragraph

Article in The International journal of eating disorders, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Nothing Tastes as Good as Thin Feels: Low Positive Emotion Differentiation and Weight Loss Activities in Anorexia Nervosa.Clinical psychological science : a journal of the Association for Psychological Science · 2014
    Article
  10. Article
  11. Primary amenorrhea in anorexia nervosa: impact on characteristic masculine and feminine traits.European eating disorders review : the journal of the Eating Disorders Association · 2014
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Understanding the association of impulsivity, obsessions, and compulsions with binge eating and purging behaviours in anorexia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2012
    Article
  17. Retrospective maternal report of early eating behaviours in anorexia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2012
    Article
  18. Depression and eating disorders: treatment and course.Journal of affective disorders · 2011
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Walter H KayeDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Cynthia M Bulik
Katherine Plotnicov
Laura Thornton
Bernie Devlin
Manfred M Fichter
Janet Treasure
Allan Kaplan
D Blake Woodside
Craig L Johnson
Katherine Halmi
Harry A Brandt
Steve Crawford
James E Mitchell
Michael Strober
Wade Berrettini
Ian Jones

Funding

Genetics of Anorexia NervosaR01MH066122 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAYE, WALTER H · 2002 to 2006
$3.1M
Genetics of Anorexia NervosaR01MH066117 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEVLIN, BERNIE · 2002 to 2006
$1.0M
Genetics of Anorexia NervosaR01MH066146 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BERRETTINI, WADE H · 2002 to 2005
$951k
Genetics of Anorexia NervosaR01MH066288 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI STROBER, MICHAEL A · 2002 to 2005
$915k
The Genetics of Anorexia NervosaR01MH066289 · NIMH · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI HALMI, KATHERINE A · 2002 to 2005
$858k
Genetics of Anorexia NervosaR01MH066147 · NIMH · LAUREATE PSYCHIATRIC CLINIC AND HOSPITAL · PI JOHNSON, CRAIG · 2002 to 2005
$857k
Genetics of Anorexia NervosaR01MH066193 · NIMH · ST. JOSEPH MEDICAL CENTER (TOWSON, MD) · PI BRANDT, HARRY A · 2002 to 2005
$839k
Genetics of Anorexia NervosaR01MH066287 · NIMH · NEUROPSYCHIATRIC RESEARCH INSTITUTE · PI MITCHELL, JAMES EDWARD · 2002 to 2005
$827k
Genetics of Anorexia NervosaR01MH066296 · NIMH · UNIVERSITY HEALTH NETWORK · PI KAPLAN, ALLAN S · 2002 to 2005
$648k
Genetics of Anorexia NervosaR01MH066145 · NIMH · KLINIK ROSENECK · PI FICHTER, MANFRED M · 2002 to 2005
$625k
NIMH NIH HHS MH066117NIMH NIH HHS MH066122NIMH NIH HHS MH066145NIMH NIH HHS MH066146NIMH NIH HHS MH066147NIMH NIH HHS MH066193NIMH NIH HHS MH066287NIMH NIH HHS MH066288NIMH NIH HHS MH066289NIMH NIH HHS MH066296NIMH NIH HHS R01 MH066117NIMH NIH HHS R01 MH066122NIMH NIH HHS R01 MH066145NIMH NIH HHS R01 MH066146NIMH NIH HHS R01 MH066147NIMH NIH HHS R01 MH066193NIMH NIH HHS R01 MH066287NIMH NIH HHS R01 MH066288NIMH NIH HHS R01 MH066289NIMH NIH HHS R01 MH066296
6 · The paper itself

Abstract

objectiveSupported by National Institute of Mental Health (NIMH), this 12-site international collaboration seeks to identify genetic variants that affect risk for anorexia nervosa (AN).

methodFour hundred families will be ascertained with two or more individuals affected with AN. The assessment battery produces a rich set of phenotypes comprising eating disorder diagnoses and psychological and personality features known to be associated with vulnerability to eating disorders.

resultsWe report attributes of the first 200 families, comprising 200 probands and 232 affected relatives.

conclusionThese results provide context for the genotyping of the first 200 families by the Center for Inherited Disease Research. We will analyze our first 200 families for linkage, complete recruitment of roughly 400 families, and then perform final linkage analyses on the complete cohort. DNA, genotypes, and phenotypes will form a national eating disorder repository maintained by NIMH and available to qualified investigators.

Indexed as

International CooperationAdolescentAdultAgedAnorexia NervosaChildFemaleGenetic LinkageGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedPhenotypeRisk Factors

Identifiers

PMID18236451
PMCPMC3755506

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.