ReviewDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2008
[Surgical trauma and postoperative immunosuppression].
Review in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Innate immunity recovers earlier than acquired immunity during severe postoperative immunosuppression.International journal of medical sciences · 2018Trial
- Disseminated Intravascular Coagulation (DIC): Old player creates new perspectives on the polymicrobial sepsis model of CASP.PloS one · 2022Article
- Anti-PD-1 Antibody Administration following Hip Fracture Surgery Reverses Immune Dysfunction and Decreases Susceptibility to Infection.Mediators of inflammation · 2019Article
- Interleukin-2 administration after modified radical mastectomy in breast cancer therapy increases peripheral regulatory T cells.International journal of clinical and experimental medicine · 2015Article
- Systemic inflammatory response after laparoscopic and conventional colectomy for cancer: a matched case-control study.Surgical endoscopy · 2012Article
- [Pathophysiological basis of surgery-linked sepsis].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2011Review
- Implantation of alloplastic material increases survival of mice subsequently exposed to polymicrobial sepsis.Langenbeck's archives of surgery · 2010Article
- Increased HMGB1 expression and release by mononuclear cells following surgical/anesthesia trauma.Critical care (London, England) · 2010Article
- Postoperative morbidity following chemoradiation for locally advanced low rectal cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Abdominal surgery is regularly followed by immune dysfunction that can last for several days. In case of septic complications during this period, there is imminent danger of mortality due to reduced immune function. This fact leads to classification of sepsis in regard to its genesis: spontaneously acquired sepsis type A is distinguishable from sepsis type B, which is acquired postoperatively. The main difference between these types is the immunologic condition at the time point of sepsis development. Postoperative immune dysfunction can be described by several parameters, i.e. reduction of HLA-DR expression on monocytes and increased apoptosis of T lymphocytes. A direct correlation exists between magnitude of immune dysfunction and complexity of the previous surgical trauma. For the first time it is now possible to study this phenomenon of postoperative immune dysfunction by use of an adequate animal model. Intestinal manipulation in mice fulfils the necessary criteria to serve as a model of surgically induced immune dysfunction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.