Ion channels: coughing up flu's proton channels.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

1. The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivatives.Chemical reviews · 2013
   Review
2. Computational study of drug binding to the membrane-bound tetrameric M2 peptide bundle from influenza A virus.Biochimica et biophysica acta · 2011
   Article
3. Where does amantadine bind to the influenza virus M2 proton channel?Trends in biochemical sciences · 2010
   Article
4. Binding hot spots and amantadine orientation in the influenza a virus M2 proton channel.Biophysical journal · 2009
   Article
5. Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins.Progress in nuclear magnetic resonance spectroscopy · 2009
   Article
6. Structure and function of the influenza A M2 proton channel.Biochemistry · 2009
   Article
7. Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel.Proceedings of the National Academy of Sciences of the United States of America · 2009
   Article
8. Immobilization of the influenza A M2 transmembrane peptide in virus envelope-mimetic lipid membranes: a solid-state NMR investigation.Biochemistry · 2009
   Article
9. Structure of amantadine-bound M2 transmembrane peptide of influenza A in lipid bilayers from magic-angle-spinning solid-state NMR: the role of Ser31 in amantadine binding.Journal of molecular biology · 2009
   Article
10. Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
11. Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel.Proceedings of the National Academy of Sciences of the United States of America · 2008
    Article

Corrections and comments

• Comment on
  Structure and mechanism of the M2 proton channel of influenza A virus.2008
• Comment on
  Structural basis for the function and inhibition of an influenza virus proton channel.2008

Authors and funding

1 author at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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