Evidence map›Paper›PMID 18234873›Full record

ArticleJournal of clinical microbiology2008

New diagnostic real-time PCR for specific detection of Parachlamydia acanthamoebae DNA in clinical samples.

Nicola Casson, Klara M Posfay-Barbe, Alain Gervaix, Gilbert Greub

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 59 citations in OpenAlex.

  1. Journal of medical microbiology · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Microorganisms · 2019
    Article
  6. Article
  7. Absence of Chlamydia-like organisms in pigs.New microbes and new infections · 2015
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Development of a real-time PCR for the specific detection of Waddlia chondrophila in clinical samples.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2009
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nicola CassonCenter for Research on Intracellular Bacteria, Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne 1011, Switzerland. gilbert.greub@chuv.ch.
Klara M Posfay-Barbe
Alain Gervaix
Gilbert Greub
University Hospital of Geneva · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the low sensitivity of amoebal coculture, we developed a specific real-time PCR for the detection of Parachlamydia. The analytical sensitivity was high, and the inter- and intrarun variabilities were low. When the PCR was applied to nasopharyngeal aspirates, it was positive for six patients with bronchiolitis. Future studies should assess the role of Parachlamydia in bronchiolitis.

Indexed as

AcanthamoebaAdolescentAnimalsBronchiolitisChild, PreschoolChlamydialesDNA, BacterialFemaleGram-Negative Bacterial InfectionsHumansInfantMalePolymerase Chain ReactionReproducibility of ResultsSensitivity and SpecificityDNA, Bacterial

Identifiers

PMID18234873
PMCPMC2292907
OpenAlexW2150762037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.