ArticleJournal of clinical microbiology2008
Diagnostic approach to acute diarrheal illness in a military population on training exercises in Thailand, a region of campylobacter hyperendemicity.
Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Prevalence and antimicrobial resistance ofOne health (Amsterdam, Netherlands) · 2025Review
- Evaluation of Fecal Inflammatory Biomarkers to Identify Bacterial Diarrhea Episodes: Systematic Review and Protocol for the Enterics for Global HealthOpen forum infectious diseases · 2024Article
- Article
- Occupations at risk of contracting zoonoses of public health significance in Québec.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021Article
- Epidemiology and etiology of Traveler's diarrhea in Bangkok, Thailand, a case-control study.Tropical diseases, travel medicine and vaccines · 2019Article
- Travelers' diarrhea: update on the incidence, etiology and risk in military and similar populations - 1990-2005 versus 2005-2015, does a decade make a difference?Tropical diseases, travel medicine and vaccines · 2019Article
- Travelers' Diarrhea in Thailand: A Quantitative Analysis Using TaqMan® Array Card.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Article
- Antibiotic resistance in Campylobacter and other diarrheal pathogens isolated from US military personnel deployed to Thailand in 2002-2004: a case-control study.Tropical diseases, travel medicine and vaccines · 2017Article
- The Periplasmic Chaperone Network ofFrontiers in microbiology · 2017Article
- Multicenter Evaluation of Clinical Diagnostic Methods for Detection and Isolation of Campylobacter spp. from Stool.Journal of clinical microbiology · 2016Article
- Detection of Campylobacter in stool and determination of significance by culture, enzyme immunoassay, and PCR in developing countries.Journal of clinical microbiology · 2014Article
- PFGE, Lior serotype, and antimicrobial resistance patterns among Campylobacter jejuni isolated from travelers and US military personnel with acute diarrhea in Thailand, 1998-2003.Gut pathogens · 2010Article
- Assessment of the duration of protection in Campylobacter jejuni experimental infection in humans.Infection and immunity · 2010Article
- The epidemiology of Guillain-Barré Syndrome in U.S. military personnel: a case-control study.BMC research notes · 2009Article
- Immune response to and histopathology of Campylobacter jejuni infection in ferrets (Mustela putorius furo).Comparative medicine · 2009Article
- Detection of Campylobacter in human faecal samples in Fiji.Western Pacific surveillance and response journal : WPSARArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High rates of Campylobacter fluoroquinolone resistance highlight the need to evaluate diagnostic strategies that can be used to assist with clinical management. Diagnostic tests were evaluated with U.S. soldiers presenting with acute diarrhea during deployment in Thailand. The results of bedside and field laboratory diagnostic tests were compared to stool microbiology findings for 182 enrolled patients. Campylobacter jejuni was isolated from 62% of the cases. Clinical and laboratory findings at the time of presentation were evaluated to determine their impact on the posttest probability, defined as the likelihood of a diagnosis of Campylobacter infection. Clinical findings, the results of tests for inflammation (stool occult blood testing [Hemoccult], fecal leukocytes, fecal lactoferrin, plasma C-reactive protein), and the numbers of Campylobacter-specific antibody-secreting cells in peripheral blood failed to increase the posttest probability above 90% in this setting of Campylobacter hyperendemicity when these findings were present. Positive results by a Campylobacter-specific commercial enzyme immunoassay (EIA) and, less so, a research PCR were strong positive predictors. The negative predictive value for ruling out Campylobacter infection, defined as a posttest probability of less than 10%, was similarly observed with these Campylobacter-specific stool-based tests as well the fecal leukocyte test. Compared to the other tests evaluated, the Campylobacter EIA is a sensitive and specific rapid diagnostic test that may assist with diagnostic evaluation, with consideration of the epidemiological setting, logistics, and cost.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.