SynthesisJournal of virology2008
Phylogenetic evidence against evolutionary stasis and natural abiotic reservoirs of influenza A virus.
Synthesis in Journal of virology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 43 citations in OpenAlex.
- Article
- Epidemiological indicators of accidental laboratory-origin outbreaks.Epidemiology and infection · 2026Review
- Evolutionary trajectory and spread of respiratory syncytial virus group A in neonatal cohorts in Pakistan amidst the COVID-19 pandemic.Scientific reports · 2025Article
- How ancient RNA survives and what we can learn from it.Nature reviews. Molecular cell biology · 2024Article
- Article
- The beginning and ending of a respiratory viral pandemic-lessons from the Spanish flu.Microbial biotechnology · 2022Article
- Climate change, melting cryosphere and frozen pathogens: Should we worry…?Environmental sustainability (Singapore) · 2021Review
- "Frozen evolution" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence.PLoS biology · 2020Article
- Glass Wool Concentration Optimization for the Detection of Enveloped and Non-enveloped Waterborne Viruses.Food and environmental virology · 2019Article
- The Diversification of Zika Virus: Are There Two Distinct Lineages?Genome biology and evolution · 2017Article
- Exploring the temporal structure of heterochronous sequences using TempEst (formerly Path-O-Gen).Virus evolution · 2016Article
- Freezing viruses in time.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- A complete ancient RNA genome: identification, reconstruction and evolutionary history of archaeological Barley Stripe Mosaic Virus.Scientific reports · 2014Article
- Local-scale diversity and between-year "frozen evolution" of avian influenza A viruses in nature.PloS one · 2014Article
- Persistence of avian influenza viruses in various artificially frozen environmental water types.Influenza research and treatment · 2012Article
- A Bayesian phylogenetic method to estimate unknown sequence ages.Molecular biology and evolution · 2011Article
- Article
- Article
- Using non-homogeneous models of nucleotide substitution to identify host shift events: application to the origin of the 1918 'Spanish' influenza pandemic virus.Journal of molecular evolution · 2009Article
- Inactivation of influenza A viruses in the environment and modes of transmission: a critical review.The Journal of infection · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Zhang et al. (G. Zhang, D. Shoham, D. Gilichinsky, S. Davydov, J. D. Castello, and S. O. Rogers, J. Virol. 80:12229-12235, 2006) have claimed to have recovered influenza A virus RNA from Siberian lake ice, postulating that ice might represent an important abiotic reservoir for the persistence and reemergence of this medically important pathogen. A rigorous phylogenetic analysis of these influenza A virus hemagglutinin gene sequences, however, indicates that they originated from a laboratory reference strain derived from the earliest human influenza A virus isolate, WS/33. Contrary to Zhang et al.'s assertions that the Siberian "ice viruses" are most closely related either to avian influenza virus or to human influenza virus strains from Asia from the 1960s (Zhang et al., J. Virol. 81:2538 [erratum], 2007), they are clearly contaminants from the WS/33 positive control used in their laboratory. There is thus no credible evidence that environmental ice acts as a biologically relevant reservoir for influenza viruses. Several additional cases with findings that seem at odds with the biology of influenza virus, including modern-looking avian influenza virus RNA sequences from an archival goose specimen collected in 1917 (T. G. Fanning, R. D. Slemons, A. H. Reid, T. A. Janczewski, J. Dean, and J. K. Taubenberger, J. Virol. 76:7860-7862, 2002), can also be explained by laboratory contamination or other experimental errors. Many putative examples of evolutionary stasis in influenza A virus appear to be due to laboratory artifacts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.