Trial reportInternational urogynecology journal and pelvic floor dysfunction2008
Duloxetine 1 year on: the long-term outcome of a cohort of women prescribed duloxetine.
Trial report in International urogynecology journal and pelvic floor dysfunction, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Considering benefits and harms of duloxetine for treatment of stress urinary incontinence: a meta-analysis of clinical study reports.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2017Pooled it
- Acupuncture for stress urinary incontinence in adults.The Cochrane database of systematic reviews · 2013Pooled it
- Effect of monopolar capacitive resistive radiofrequency in treating stress urinary incontinence: A pilot randomized control trial.Frontiers in psychology · 2022Article
- Clinical study of effectiveness and safety of CELcomplexJournal of traditional and complementary medicine · 2019Article
- Mixed urinary incontinence: international urogynecological association research and development committee opinion.International urogynecology journal · 2014Review
- Use of symptom-relieving drugs before and after surgery for urinary incontinence in women: a cohort study.BMJ open · 2013Article
- [Stress incontinence in elderly women].Der Urologe. Ausg. A · 2013Article
- Management of urinary incontinence.P & T : a peer-reviewed journal for formulary management · 2012Article
- Nonsurgical outpatient therapies for the management of female stress urinary incontinence: long-term effectiveness and durability.Advances in urology · 2011Article
- Analytic model comparing the cost utility of TVT versus duloxetine in women with urinary stress incontinence.International urogynecology journal · 2010Article
- Update on duloxetine for the management of stress urinary incontinence.Clinical interventions in aging · 2009Review
Corrections and comments
- Commented on by
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This aim of this study was to determine the long-term persistence with duloxetine in a cohort of women treated for stress incontinence and any alternative treatments undertaken. Two hundred twenty-eight women prescribed duloxetine were initially reviewed after 4 weeks of treatment. Women continuing therapy were reassessed at 4 and 6 months and 1 year with a review of all treatments after 1 year. At each visit, they were asked about persistence with duloxetine, reasons for discontinuation and any alternative treatments. Seventy-one (31%) women continued beyond 4 weeks of treatment, and twenty-six (12%) were taking duloxetine 4 months later, 23 (10%) at 6 months and 21 (9%) at 1 year. One year later, 187 (82%) women had a tension-free vaginal tape operation (TVT). The majority of women discontinued because of side effects (56%) or lack of efficacy (33%). Few women persevere with duloxetine beyond 4 months. One year later, the majority of women had a TVT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.