Evidence map›Paper›PMID 18230864›Full record

Trial reportJournal of speech, language, and hearing research : JSLHR2008

A randomized study of three interventions for aspiration of thin liquids in patients with dementia or Parkinson's disease.

Jeri A Logemann, Gary Gensler, Joanne Robbins, Anne S Lindblad, Diane Brandt, Jacqueline A Hind, Steven Kosek, Karen Dikeman, Marta Kazandjian, Gary D Gramigna and 3 more

3 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of speech, language, and hearing research : JSLHR, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 141 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 12 pooled it
39.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03017079 nacompletednot on this mapstarted 2016, after this paper: background citation

A More Physiological Feeding Process in ICU:the Intermittent Infusion With Semi-solidification of Nutrients

TypeinterventionalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2016 to 2017Enrolled40ConditionsNutrition, EnteralArmssemi-solid agent with standard enteral feeding, standard enteral feeding
NCT03682081 nacompletednot on this mapstarted 2020, after this paper: background citation

Impact of Novel Rehabilitative Approaches for Dysphagia in Patients With Alzheimer's Disease and Related Dementias

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2020 to 2025Enrolled76ConditionsDementia, Dysphagia, Alzheimer DiseaseArmsIsometric tongue strengthening facilitated by Iowa Oral Performance Instrument (IOPI), Biotene Oral Balance Gel
NCT05108896 narecruitingnot on this mapstarted 2021, after this paper: background citation

Aspiration in Acute Respiratory Failure Survivors

TypeinterventionalSponsorUniversity of Colorado, DenverRan2021 to 2025Enrolled855ConditionsDysphagia, AspirationArms3-Screenings Protocol, FEES, Tracheal Ultrasound
3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 12 syntheses or guidelines pooled it, 410 citations in OpenAlex.

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  9. Treatment for dysphagia (swallowing difficulties) in hereditary ataxia.The Cochrane database of systematic reviews · 2015
    Pooled it
  10. Efficacy of thickened liquids for eliminating aspiration in head and neck cancer: a systematic review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2015
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  15. How a personalised transportable folding device for seating impacts dysphagia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020
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81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Jeri A LogemannDepartment of Communication Sciences and Disorders, Northwestern University, 2240 Campus Drive, #3-358, Evanston, IL 60208, USA. j-logemann@northwestern.edu
Gary Gensler
Joanne Robbins
Anne S Lindblad
Diane Brandt
Jacqueline A Hind
Steven Kosek
Karen Dikeman
Marta Kazandjian
Gary D Gramigna
Donna Lundy
Susan McGarvey-Toler
Patricia J Miller Gardner
Google (United States) · USEmmes (United States) · USNew York Hospital Queens · USRichard L. Roudebush VA Medical Center · USWilliam S. Middleton Memorial Veterans Hospital · US

Funding

ZOSUQUIDAR TRIHYDROCHLORIDE IN NEWLY DIAGNOSED AMLM01RR003186 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI MATLOUB, YOUSIF H · 1986 to 2007
$19.3M
ASHA CLINICAL TRIALS COOPERATIVE GROUPSU01DC003206 · NIDCD · AMERICAN SPEECH-LANGUAGE-HEARING ASSN · PI LOGEMANN, JERILYN A · 1997 to 2004
$4.3M
NCRR NIH HHS M01 RR003186NIDCD NIH HHS U01 DC003206
6 · The paper itself

Abstract

purposeThis study was designed to identify which of 3 treatments for aspiration on thin liquids-chin-down posture, nectar-thickened liquids, or honey-thickened liquids-results in the most successful immediate elimination of aspiration on thin liquids during the videofluorographic swallow study in patients with dementia and/or Parkinson's disease.

methodThis randomized clinical trial included 711 patients ages 50 to 95 years who aspirated on thin liquids as assessed videofluorographically. All patients received all 3 interventions in a randomly assigned order during the videofluorographic swallow study.

resultsImmediate elimination of aspiration on thin liquids occurred most often with honey-thickened liquids for patients in each diagnostic category, followed by nectar-thickened liquids and chin-down posture. Patients with most severe dementia exhibited least effectiveness on all interventions. Patient preference was best for chin-down posture followed closely by nectar-thickened liquids.

conclusionTo identify best short-term intervention to prevent aspiration of thin liquid in patients with dementia and/or Parkinson's disease, a videofluorographic swallow assessment is needed. Evidence-based practice requires taking patient preference into account when designing a dysphagic patient's management plan. The longer-term impact of short-term prevention of aspiration requires further study.

Indexed as

PostureAgedAged, 80 and overDeglutitionDeglutition DisordersDementiaFemaleFluoroscopyHumansMaleMiddle AgedMultivariate AnalysisParkinson DiseasePneumonia, AspirationSolutionsSolutions

Identifiers

PMID18230864
PMCPMC2894528
OpenAlexW2052570888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.