ArticleEvidence-based complementary and alternative medicine : eCAM2007
Acupuncture regulates leukocyte subpopulations in human peripheral blood.
Article in Evidence-based complementary and alternative medicine : eCAM, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of acupoint stimulation as an adjunct therapy for lung cancer: a systematic review and meta-analysis.BMC complementary and alternative medicine · 2013Pooled it
- Effect of acupuncture in myelosuppression and quality of life in women with breast cancer undergoing chemotherapy: a randomized clinical study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Trial
- Impact of electroacupuncture on quality of life for patients with Relapsing-Remitting Multiple Sclerosis under treatment with immunomodulators: a randomized study.BMC complementary and alternative medicine · 2012Trial
- Effects of some acupoints (Du-14, Li-11, St-36, and Sp-6) on serum TNF-α and hsCRP levels in healthy young subjects.Journal of alternative and complementary medicine (New York, N.Y.) · 2011Trial
- Revolutionizing the understanding of acupoint biology and acupuncture mechanisms through spatial omics: current perspectives and future directions.Frontiers in medicine · 2026Review
- The immunomodulatory mechanisms for acupuncture practice.Frontiers in immunology · 2023Review
- Biomedicine and traditional Chinese medicine: a fruitful scientific and cultural interaction.Acta bio-medica : Atenei Parmensis · 2022Article
- Efficacy and Safety of Acupuncture on Symptomatic Improvement in Primary Sjögren's Syndrome: A Randomized Controlled Trial.Frontiers in medicine · 2022Article
- Recovery of a patient with severe COVID-19 by acupuncture and Chinese herbal medicine adjuvant to standard care.Journal of integrative medicine · 2021Article
- Effect of Electroacupuncture on Natural-Killer Cells and Tumor Size in Patients with Cervical Squamous-Cell Carcinoma: A Randomized Controlled Trial.Medical acupuncture · 2019Article
- Immune Modulation and Treatment of Human Papilloma Virus-Related Warts with Energetics of Living Systems Acupuncture.Medical acupuncture · 2017Article
- Electro-Acupuncture Therapy Increases Serum Interferon-γ Levels in Rats with 7, 12 Dimethylbenz(α)anthracene (DMBA)-Induced Breast TumorsAsian Pacific journal of cancer prevention : APJCP · 2017Article
- Effect of Acupuncture on Endometrial Angiogenesis and Uterus Dendritic Cells in COH Rats during Peri-Implantation Period.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- Efficacy and safety of acupuncture for chemotherapy-induced leucopoenia: protocol for a systematic review.BMJ open · 2016Article
- Acupuncture as anticancer treatment?Contemporary oncology (Poznan, Poland) · 2016Review
- Effect of Acupuncture on Body Weight Reduction and Inflammatory Mediators in Egyptian Obese Patients.Open access Macedonian journal of medical sciences · 2015Article
- Effects of acupuncture on leucopenia, neutropenia, NK, and B cells in cancer patients: a randomized pilot study.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Effects of acupuncture for cancer pain and quality of life - a case series.Chinese medicine · 2013Article
- Acupuncture May Stimulate Anticancer Immunity via Activation of Natural Killer Cells.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Damage of splenic T lymphocyte proliferation and differentiation and its normalization by electroacupuncture in morphine-dependent mice mode.Evidence-based complementary and alternative medicine : eCAM · 2011Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acupuncture has recently been attracting more and more people throughout the world as an alternative treatment, however little is known about its physiological activities (i.e. immune system). We examined acupuncture both quantitatively and qualitatively by measuring CD-positive cell counts and cytokine expression levels in the blood, to determine the activity of T cells, B cells, macrophages and natural killer (NK) cells. Fifteen milliliters of peripheral blood obtained from 17 healthy volunteers aged 21-51 years, were analyzed using flow cytometry before and after acupuncture treatment. There was a statistically significant increase in the number of CD2(+), CD4(+), CD8(+), CD11b(+), CD16(+), CD19(+), CD56(+) cells as well as IL-4, IL-1beta and IFN-gamma levels in the cells after acupuncture stimulation of meridian points. These observations indicate that acupuncture may regulate the immune system and promote the activities of humoral and cellular immunity as well as NK cell activity. In this article, we discussed how acupuncture regulated leukocyte numbers and functions since they are considered to be potential indicators for evaluating complementary and alternative medicine.
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