ArticleThe international journal of cardiovascular imaging2008
A relationship between echocardiographic subepicardial adipose tissue and metabolic syndrome.
Article in The international journal of cardiovascular imaging, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Epicardial fat: definition, measurements and systematic review of main outcomes.Arquivos brasileiros de cardiologia · 2013Pooled it
- Evaluation of risk factors associated with epicardial fat tissue thickness in patients with stage 4 and stage 5 chronic kidney disease.International urology and nephrology · 2025Article
- Epicardial and Perihepatic Fat as Cardiometabolic Risk Predictors in Girls with Turner Syndrome: A Cardiac Magnetic Resonance StudyJournal of clinical research in pediatric endocrinology · 2021Article
- Cardiac Adiposity and Arrhythmias: The Role of Imaging.Diagnostics (Basel, Switzerland) · 2021Review
- Atherosclerosis in chronic hepatitis C virus patients with and without liver cirrhosis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2017Article
- Epicardial Adipose Tissue Removal Potentiates Outward Remodeling and Arrests Coronary Atherogenesis.The Annals of thoracic surgery · 2017Article
- Epicardial Fat: Physiological, Pathological, and Therapeutic Implications.Cardiology research and practice · 2016Review
- Review
- Evaluation of epicardial adipose tissue in familial partial lipodystrophy.Diabetology & metabolic syndrome · 2015Article
- Epicardial adiposity in children with obesity and metabolic syndrome.Iranian journal of pediatrics · 2014Article
- The relationship between epicardial fat thickness and gestational diabetes mellitus.Diabetology & metabolic syndrome · 2014Article
- Epicardial adipose tissue thickness and plasma homocysteine in patients with metabolic syndrome and normal coronary arteries.Diabetology & metabolic syndrome · 2014Article
- Relationship of epicardial adipose tissue thickness with early indicators of atherosclerosis and cardiac functional changes in obese adolescents with metabolic syndrome.Journal of clinical research in pediatric endocrinology · 2013Article
- Relation of epicardial fat thickness with carotid intima-media thickness in patients with type 2 diabetes mellitus.International journal of endocrinology · 2013Article
- Subepicardial adipose tissue thickness and its relation with anthropometric and clinical parameters in pubertal obese children.Journal of endocrinological investigation · 2010Article
- The Association of Epicardial Adipose Tissue and the Metabolic Syndrome in Community Participants in South Africa.Journal of cardiovascular echographyArticle
- Link between Yoga and Heart Rate Variability: Can Yoga Enhance the Cardiac Resonance.International journal of yogaReview
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVisceral adipose tissue plays a central role in the development of metabolic syndrome (MS). Our study aimed to determine a relationship between MS and subepicardial adipose tissue (SAT), a component of visceral fat surrounding the heart and coronary vessels.
methodsA total of 123 patients (54 +/- 10 years of age, 47 male patients) diagnosed with MS and 123 age- and gender-matched control subjects were evaluated echocardiographically. Thickness of the SAT was measured using M-mode echocardiography in parasternal long and short axis views. Maximum values at any site were measured, and the average value was used for statistical analyses. Metabolic syndrome was identified according to the latest criteria of International Diabetes Federation.
resultsThe patients with MS had significantly higher SAT thickness compared to the subjects in the control group (5.1 +/- 1.7 vs. 3.4 +/- 1.6 mm, P < 0.001). A stepwise increase was noted in the SAT thickness depending on the number of the MS components (P < 0.001). The multivariate stepwise linear regression analysis revealed that the diagnosis of MS (t = 3.019, P = 0.001), serum triglyceride level (t = 3.423, P = 0.001), gender (t = -5.507, P < 0.001), age (t = 2.394, P = 0.02) and waist circumference (t = 9.656, P < 0.001) were the independent determinants of SAT thickness. For each 10 and 20-cm increase in waist circumference, 0.094 and 0.19-mm increases in SAT thickness were expected. As an optimal cut off point, 4.35 mm SAT thickness have determined metabolic syndrome with a 61.7% sensitivity and 79.2% specificity.
conclusionsA close relationship between SAT thickness and MS was demonstrated. Assessment of SAT thickness in routine echocardiographic examinations might be used in predicting the existence of MS and its associated cardiovascular risks.
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