ArticleEuropean radiology2008
Value of automatic bone subtraction in cranial CT angiography: comparison of bone-subtracted vs. standard CT angiography in 100 patients.
Article in European radiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Subtracted 3D CT angiography for the evaluation of intracranial aneurysms in 256-slice multidetector CT: usefulness of the 80-kVp plus compact contrast medium bolus protocol.European radiology · 2013Trial
- Optimizing contrast protocol for bone-subtraction CT angiography of intracranial arteries in normal dogs using 160-slice CT.Veterinary medicine and science · 2023Article
- Comparison of bone subtraction CT angiography with standard CT angiography for evaluating circle of Willis in normal dogs.Journal of veterinary science · 2023Article
- Emergent neurovascular imaging in patients with blunt traumatic injuries.Frontiers in radiology · 2022Review
- Ultra-high-resolution subtraction CT angiography in the follow-up of treated intracranial aneurysms.Insights into imaging · 2019Article
- Subtraction CT angiography in head and neck with low radiation and contrast dose dual-energy spectral CT using rapid kV-switching technique.The British journal of radiology · 2018Article
- Advances in the Study of the Middle Cranial Fossa through Cutting Edge Neuroimaging Techniques.Journal of medical systems · 2018Article
- Diagnostic Impact of Bone-Subtraction CT Angiography for Patients with Acute Subarachnoid Hemorrhage.AJNR. American journal of neuroradiology · 2016Article
- The role of bone subtraction computed tomographic angiography in determining intracranial aneurysms in non-traumatic subarachnoid hemorrhage.Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society · 2014Article
- Effect of region-of-interest placement in bolus tracking cerebral computed tomography angiography.Neuroradiology · 2013Article
- Semi-automatic quantitative measurements of intracranial internal carotid artery stenosis and calcification using CT angiography.Neuroradiology · 2012Article
- Subtraction CT angiography for evaluation of intracranial aneurysms: comparison with conventional CT angiography.European radiology · 2009Article
- [Neurologic emergencies and multislice computed tomography].Der Radiologe · 2009Review
- Dual-Energy CT: What the Neuroradiologist Should Know.Current radiology reportsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-contrast-enhanced cranial computed tomography (NECT) and CT angiography (CTA) are the most frequently used modalities in the triage of patients with acute ischemic and hemorrhagic stroke. CTA bone removal can improve the delineation of vasculature closely adjacent to bony structures, which is sometimes limited in standard CTA. The aim of this study was the evaluation of the clinical benefit of bone subtraction (BS) regarding delineation of cerebral vasculature, reading time and depiction of vascular pathologies compared to standard CTA without BS. A total of 100 patients who underwent NECT and supraaortic CTA on a 64-slice CT system were retrospectively included in the study. Bone removal was performed by subtraction of the NECT data from the CTA data using a dedicated workstation. Standard and BS CTA of each patient was reviewed for delineation of cerebral vasculature (grading scale from 1 = "excellent delineation" to 10 = "hardly any delineation"), reading time and depiction of vascular pathologies (standardized catalog) by two blinded readers. For BS data sets, the quality of BS was rated by a combination of the criteria complete bone removal, depiction of vascular structures and sufficient quality for diagnostic evaluation. The use of BS significantly reduced reading time from 4.60 min to 3.49 min (p<0.001). Performing BS, the quality of vascular delineation of the cerebral arteries, cerebral veins and cavernous segment of the ICA increased significantly as compared to standard CTA (1.70 vs. 2.70; 2.60 vs. 4.12; 2.35 vs. 4.40, all p<0.001). Consensus reading showed 41 pathologies in 35 patients. Diagnosis was missed or wrong overall in 15 cases, with 3 missed aneurysms (CTA: 2 vs. BS: 1), 8 wrong stenotic findings (CTA: 3 vs. BS: 5) and 4 missed partial thromboses (CTA: 2 vs. BS: 2). Performing BS in supraaortic CTA for the evaluation of cerebral vasculature reduces reading time and improves delineation of vessels. Diagnostic accuracy in general is not improved by BS, as the diagnostic accuracy of stenotic vessel alterations is reduced by potential truncation artifacts, but the detection rate of cerebral aneurysms slightly increases.
Indexed as
Identifiers
18224325What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.