ReviewTherapeutic drug monitoring2008
Triptans in pregnancy.
Review in Therapeutic drug monitoring, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Headache and pregnancy: a systematic review.The journal of headache and pain · 2017Pooled it
- Review
- Pharmacological Management of Orofacial Pain.Drugs · 2023Review
- Perinatal use of triptans and other drugs for migraine-A nationwide drug utilization study.PloS one · 2021Article
- Protective Roles of N-acetyl Cysteine and/or Taurine against Sumatriptan-Induced Hepatotoxicity.Advanced pharmaceutical bulletin · 2016Article
- Eletriptan in the management of acute migraine: an update on the evidence for efficacy, safety, and consistent response.Therapeutic advances in neurological disorders · 2016Review
- Pharmacological treatment of migraine during pregnancy and breastfeeding.Nature reviews. Neurology · 2015Review
- Headache in pregnancy: an approach to emergency department evaluation and management.The western journal of emergency medicine · 2015Review
- Sex-related differences in migraine.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2014Review
- Migraine in pregnancy and lactation.Current neurology and neuroscience reports · 2014Review
- Migraine and preterm birth.Journal of perinatology : official journal of the California Perinatal Association · 2011Article
- Acute neurological issues in pregnancy and the peripartum.The Neurohospitalist · 2011Article
- Safety of triptans for migraine headaches during pregnancy and breastfeeding.Canadian family physician Medecin de famille canadien · 2010Article
- Clinical review of headache in pregnancy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2010Review
- Medication use in the treatment of migraine during pregnancy and lactation.Current pain and headache reports · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The triptans are a class of tryptamine-based drugs indicated for in the treatment of migraine headaches. The triptans act as serotonin (5-hydroxytriptamine) (5-HT) agonists by binding to various serotonin receptors, causing vasoconstriction and neuronal inhibition to alleviate migraines. There are 7 types of triptans currently available on the U.S. market: almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan and zolmitriptan. The objective of this study was to examine the use and effects of triptans in pregnancy. Although three of the triptans have pregnancy registries maintained by the manufacturer, triptan use in pregnancy has not been extensively studied. Information on the use of sumatriptan during pregnancy is relatively more abundant, because it has been on the market longer than the other triptans and may also have a higher percentage of the market share. There are no data to suggest teratogenicity for any of the triptans, although preterm birth rates appear to be elevated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.