Evidence map›Paper›PMID 18223038›Full record

ArticleThe Plant cell2008

Requirement of B2-type cyclin-dependent kinases for meristem integrity in Arabidopsis thaliana.

Stig Uggerhøj Andersen, Sabine Buechel, Zhong Zhao, Karin Ljung, Ondrej Novák, Wolfgang Busch, Christoph Schuster, Jan U Lohmann

Open access · hybridAbstract read
In one paragraph

Article in The Plant cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
21.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 196 citations in OpenAlex.

  1. Article
  2. Different Dynamics:Biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Light signal regulates endoreduplication and tomato fruit expansion through the SlPIF1a-SlTLFP8-SlCDKB2 module.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Root-specific photoreception directs early root development by HY5-regulated ROS balance.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Genetic robustness control of auxin output in priming organ initiation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Stig Uggerhøj AndersenMax Planck Institute for Developmental Biology, AG Lohman, D-72076, Tübingen, Germany.
Sabine Buechel
Zhong Zhao
Karin Ljung
Ondrej Novák
Wolfgang Busch
Christoph Schuster
Jan U Lohmann
Lohmann (Germany) · DECzech Academy of Sciences, Institute of Experimental Botany · CZMax Planck Institute for Developmental Biology · DESwedish University of Agricultural Sciences · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To maintain proper meristem function, cell division and differentiation must be coordinately regulated in distinct subdomains of the meristem. Although a number of regulators necessary for the correct organization of the shoot apical meristem (SAM) have been identified, it is still largely unknown how their function is integrated with the cell cycle machinery to translate domain identity into correct cellular behavior. We show here that the cyclin-dependent kinases CDKB2;1 and CDKB2;2 are required both for normal cell cycle progression and for meristem organization. Consistently, the CDKB2 genes are highly expressed in the SAM in a cell cycle-dependent fashion, and disruption of CDKB2 function leads to severe meristematic defects. In addition, strong alterations in hormone signaling both at the level of active hormones and with respect to transcriptional and physiological outputs were observed in plants with disturbed CDKB2 activity.

Indexed as

ArabidopsisArabidopsis ProteinsCell CycleCyclin-Dependent KinasesDNA, PlantGene Expression Regulation, PlantMeristemPhenotypePlant Growth RegulatorsPlant RootsSeedlingsSignal TransductionArabidopsis ProteinsCDKB2;1 protein, ArabidopsisCDKb2;2 protein, ArabidopsisCyclin-Dependent KinasesDNA, PlantPlant Growth Regulators

Identifiers

PMID18223038
PMCPMC2254925
OpenAlexW2167855068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.